2. Academic Validation
  3. Flavonoids isolated from the fresh sweet fruit of Averrhoa carambola, commonly known as star fruit

Flavonoids isolated from the fresh sweet fruit of Averrhoa carambola, commonly known as star fruit

  • Phytochemistry. 2018 Sep:153:156-162. doi: 10.1016/j.phytochem.2018.06.007.
Xuchao Jia 1,  Haihui Xie 2,  Yueming Jiang 3,  Xiaoyi Wei 3
Affiliations

Affiliations

  • 1 Guangdong Provincial Key Laboratory of Applied Botany, Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China; Key Laboratory of Functional Foods, Ministry of Agriculture, Guangdong Key Laboratory of Agricultural Products Processing, Sericultural & Agri-food Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510610, China; University of Chinese Academy of Sciences, Beijing 100049, China.
  • 2 Guangdong Provincial Key Laboratory of Applied Botany, Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China. Electronic address: [email protected].
  • 3 Guangdong Provincial Key Laboratory of Applied Botany, Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China.
PMID: 29980108 DOI: 10.1016/j.phytochem.2018.06.007
Abstract

Thirteen Flavonoids were isolated from the fresh sweet fruit of Averrhoa carambola L. (Oxalidaceae), commonly known as star fruit, and their structures were determined by spectroscopic and chemical methods. 8-Carboxymethyl-(+)-epicatechin methyl ester, pinobanksin 3-O-β-d-glucoside, and carambolasides M-Q were undescribed structures. (+)-Epicatechin, aromadendrin 3-O-β-d-glucoside, helicioside A, taxifolin 3'-O-β-d-glucoside, galangin 3-O-rutinoside, and isorhamnetin 3-O-rutinoside were reported from this species for the first time. Pinobanksin 3-O-β-d-glucoside and carambolasides M-Q showed more potent 2,2'-azinobis-(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) radical cation scavenging activity (IC50 = 5.3-2.3 μM) than l-ascorbic acid (10.5 μM). Further, (+)-epicatechin, pinobanksin 3-O-β-d-glucoside, isorhamnetin 3-O-rutinoside, and carambolasides O-Q exhibited weak porcine pancreatic Lipase inhibitory activity.

Keywords

(+)-Epicatechin (PubChem CID: 182232); Antioxidant activity; Averrhoa carambola L. (Oxalidaceae); Dihydrokaempferol (aromadendrin) 3-O-glucoside (PubChem CID: 10478918); Flavonoid; Galangin 3-O-rutinoside (PubChem CID: 98464939); Isorhamnetin 3-O-rutinoside (PubChem CID: 17751019); Pancreatic lipase inhibition; Star fruit; Taxifolin 3′-O-glucoside (PubChem CID: 14282774).

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