Gimatecan-d5
Gimatecan-d5 (ST1481-d5) is the deuterated-labeled Gimatecan (HY-B0063). Gimatecan (ST1481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity.
For research use only. We do not sell to patients.
- Formula: C25H20D5N3O5
- Molecular Weight:452.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Topoisomerase Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 292618-32-7
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Molecular Weight 452.51
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Formula C25H20D5N3O5
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SMILES
CC(C)(C)O/N=C/C1=C2C(C(N3C2)=CC([C@@]4(O)C([2H])([2H])C([2H])([2H])[2H])=C(COC4=O)C3=O)=NC5=CC=CC=C15
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Synonyms
ST1481-d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)