292618-32-7
292618-32-7
Chemical Structure
Gimatecan
Synonym(s): ST1481
- CAS No.: 292618-32-7
- Formula:C25H25N3O5
- Molecular Weight:447.48
IUPAC Name: (S,E)-4-ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-11-carbaldehyde O-(tert-butyl) oxime
InChIKey: UIVFUQKYVFCEKJ-OPTOVBNMSA-N
SMILES: CC(C)(C)O/N=C/C1=C2C(C(N3C2)=CC([C@@]4(O)CC)=C(COC4=O)C3=O)=NC5=CC=CC=C15
Biological Activity: Gimatecan (ST1481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Gimatecan | 99.28% | Gimatecan (ST1481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity. | ||||||||||||||||||||
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Gimatecan-d5 | Gimatecan-d5 (ST1481-d5) is the deuterated-labeled Gimatecan (HY-B0063). Gimatecan (ST1481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity. | |||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.87
HY-14821Namitecan -
Similarity Score 0.80
HY-N2108R7-Ethylcamptothecin (Standard) -
Similarity Score 0.79
HY-1591627-(2-Aminoethyl)camptothecin -
Similarity Score 0.78
HY-14812Karenitecin -
Similarity Score 0.78
HY-174151XSJ110 -
Similarity Score 0.78
HY-W7402217-Ethylcamptothecin-d3-1 -
Similarity Score 0.77
HY-13566ABelotecan hydrochloride -
Similarity Score 0.77
HY-13566RBelotecan (Standard) -
Similarity Score 0.75
HY-161970XSJ05 -
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