XSJ05
XSJ05 is a camptothecin (CPT) derivative that can inhibit topoisomerase I (Topo I) to exert anti-cancer activity. XSJ05 can trigger DNA double-strand breaks, leading to DNA damage. XSJ05 can inhibit the growth of colorectal cancer (CRC), arrest the cell cycle in G2/M phase, and induce apoptosis.
For research use only. We do not sell to patients.
- CAS No.: 1461652-87-8
- Formula: C29H25N5O4S
- Molecular Weight:539.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Topoisomerase Isoforms
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Biological Activity
Chemical Information
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CAS No. 1461652-87-8
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Molecular Weight 539.60
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Formula C29H25N5O4S
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SMILES
CC1=CC=C(NC(N/N=C\C2=C3C(C(N4C3)=CC([C@](CC)(O)C(OC5)=O)=C5C4=O)=NC6=CC=CC=C26)=S)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)