High-affinity kainate and domoate receptors in rat brain

  • FEBS Lett. 1992 Jul 28;307(2):139-43. doi: 10.1016/0014-5793(92)80753-4.
H Lomeli  1 ,  W Wisden ,  M Köhler ,  K Keinänen ,  B Sommer ,  P H Seeburg
Affiliations
  • 1. Laboratory of Molecular Neuroendocrinology, Heidelberg University, Germany.
PMID: 1322826 DOI: 10.1016/0014-5793(92)80753-4
Abstract

Mammalian brain expresses receptors which bind the potent neurotoxins, kainate and domoate, with high affinity, and which form a subclass of ionotropic glutamate receptors. A new member of these receptors, expressed in both adult and embryonic CNS is compared in its ligand binding properties to its closely sequence-related homologs.