35 Results for "

(22R

" in MedChemExpress (MCE) Product Catalog:
Products (35)

35 Results for "(22R" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P77969
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IL22RA1; Interleukin 22 Receptor, Alpha 1; Prev. IL22R; IL-22R-Alpha-1; CRF2-9; IL-22RA1; Interleukin-22 Receptor Subunit Alpha-1; ZcytoR11; Cytokine Receptor Class-II Member 9; Interleukin 22 Receptor; Cytokine Receptor Family 2 Member 9; IL22R1; Interle
Species:  
Source:  
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Cat. No.: HY-P99917
CAS No.: 2200269-84-5
Synonyms: F-652; rhIL-22 dimer

Target:  

STAT

Research Areas:  

Infection Inflammation/Immunology

Eflepedocokin alfa is a recombinant fusion protein. Eflepedocokin alfa consists of human IL-22 fused to human IgG2-Fc domain. Eflepedocokin alfa leads to the activation of IL-22/IL-22R-mediated signal transduction pathways as well as STAT3. Eflepedocokin alfa plays a role in immune response and bacterial infection, enhancing intestinal barrier function, intestinal immunity, and tissue repair .
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Cat. No.: HY-116969
CAS No.: 17954-98-2
Purity:  ≥98.0%
Synonyms: Narthesterol
Target:  

LXR

Research Areas:  

Metabolic Disease

22(R)-Hydroxycholesterol (Narthesterol) is an endogenous LXR agonist. 22(R)-Hydroxycholesterol (Narthesterol) can be used for tangier disease research .
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Cat. No.: HY-125922
CAS No.: 51372-29-3
Synonyms: (22R)-BUD
(22R)-Budesonide ((22R)-BUD) is the (22R)-enantiomer of Budesonide (HY-13580). (22R)-Budesonide is a non-halogenated glucocorticoid with high local anti-inflammatory activity .
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Cat. No.: HY-117580
CAS No.: 13951-70-7
Synonyms: OH-PRED
Target:  

Drug Metabolite

Research Areas:  

Inflammation/Immunology

16α-Hydroxyprednisolone (OH-PRED) is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid Budesonide (HY-13580). 16α-Hydroxyprednisolone formation is catalyzed by isoenzymes within the cytochrome P450 3A (CYP3A) subfamily. 16α-Hydroxyprednisolone formation can be inhibited by antibodies targeting the CYP3A subfamily .
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Cat. No.: HY-W007978
CAS No.: 18741-85-0
Synonyms: R-(-)-2,2-Diamino-1,1-binaphthyl
Research Areas:  

Others

(R)-[1,1'-Binaphthalene]-2,2'-diamine is the isomer of (S)-[1,1'-Binaphthalene]-2,2'-diamine (HY-W007978A), and can be used as an experimental control. (S)-[1,1'-Binaphthalene]-2,2'-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-I0718
CAS No.: 39648-67-4
(R)-(-)-1,1'-Binaphthyl-2,2'-diyl Hydrogenphosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-75975
CAS No.: 446292-07-5
Synonyms: 1H-Isoindole-1,3(2H)-dione,2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl
Target:  

Drug Intermediate

Research Areas:  

Others

(R)-2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione (1H-Isoindole-1,3(2H)-dione,2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl) is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-125922S
Synonyms: Dexbudesonide-d6; (22R)-BUD-d6
(22R)-Budesonide-d6 (Dexbudesonide-d6) is deuterium labeled (22R)-Budesonide. (22R)-Budesonide ((22R)-BUD) is the (22R)-enantiomer of Budesonide (HY-13580). (22R)-Budesonide is a non-halogenated glucocorticoid with high local anti-inflammatory activity .
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Cat. No.: HY-137178
CAS No.: 596-94-1
20α,22R-Dihydroxycholesterol is an endogenous metabolic intermediate. 20α,22R-Dihydroxycholesterol involved in the biosynthesis of cholesterol to steroid hormones .
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Cat. No.: HY-166480S
CAS No.: 85128-75-2
Synonyms: (22R)-BUD-d8
(22R)-Budesonide-d8 ((22R)-BUD-d8) is the deuterium labeled (22R)-Budesonide. (22R)-Budesonide ((22R)-BUD) is the (22R)-enantiomer of Budesonide (HY-13580). (22R)-Budesonide is a non-halogenated glucocorticoid with high local anti-inflammatory activity .
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Cat. No.: HY-116969S
CAS No.: 1246302-93-1
Synonyms: Narthesterol-d7
22(R)-Hydroxycholesterol-d7 is deuterium labeled 22(R)-Hydroxycholesterol.
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Cat. No.: HY-117580S
Synonyms: OH-PRED-d3
16α-Hydroxyprednisolone-d3 is the deuterium labeled 16α-Hydroxyprednisolone. 16α-Hydroxyprednisolone is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid Budesonide (HY-13580). 16α-Hydroxyprednisolone formation is catalyzed by isoenzymes within the cytochrome P450 3A (CYP3A) subfamily. 16α-Hydroxyprednisolone formation can be inhibited by antibodies targeting the CYP3A subfamily .
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Cat. No.: HY-117580R
CAS No.: 13951-70-7
Synonyms: OH-PRED (Standard)
16α-Hydroxyprednisolone (OH-PRED) (Standard) is the analytical standard of 16α-Hydroxyprednisolone. This product is intended for research and analytical applications. 16α-Hydroxyprednisolone is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid Budesonide (HY-13580). 16α-Hydroxyprednisolone formation is catalyzed by isoenzymes within the cytochrome P450 3A (CYP3A) subfamily. 16α-Hydroxyprednisolone formation can be inhibited by antibodies targeting the CYP3A subfamily .
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Cat. No.: HY-146463
CAS No.: 2923738-92-3
Research Areas:  

Infection

NusB-IN-1 (Compound 22r) is a potent, orally active bacterial rRNA synthesis inhibitor. NusB-IN-1 shows antimicrobial activity against MRSA and VRSA . NusB-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-119196
CAS No.: 4952-56-1
Synonyms: SP-233
Research Areas:  

Others

Caprospinol (SP-233) is a steroid compound candidate based on the structure of 22R-hydroxycholesterol. It has multiple mechanisms of neuroprotection, including binding to β-amyloid protein (Aβ(42)), interacting with the mitochondrial respiratory chain, clearing Aβ(42) monomers, and acting as a σ-1 receptor ligand. It can cross the blood-brain barrier in vivo and restore cognitive impairment, and has the potential to inhibit Alzheimer's disease.
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Cat. No.: HY-N17585
CAS No.: 928840-27-1
Target:  

Others

Lanost-8-ene-3b,22R,24S-triol (compound 7) is a lanostane-type triterpenoid. Lanost-8-ene-3b,22R,24S-triol can be found in the sclerotia of Inonotus obliquus (Alaskan chaga) .
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Cat. No.: HY-117580S2
Synonyms: OH-PRED-d5
16α-Hydroxyprednisolone-d5 (OH-PRED-d5) is the deuterium labeled 16α-Hydroxyprednisolone (HY-117580). 16α-Hydroxyprednisolone (OH-PRED) is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid Budesonide (HY-13580). 16α-Hydroxyprednisolone formation is catalyzed by isoenzymes within the cytochrome P450 3A (CYP3A) subfamily. 16α-Hydroxyprednisolone formation can be inhibited by antibodies targeting the CYP3A subfamily .
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Cat. No.: HY-184781S
(S)-2,5,7,8-Tetramethyl-2-((2R,4R)-2,4,6-trimethylheptyl)chroman-6-ol-d11 is the deuterium labeled (S)-2,5,7,8-Tetramethyl-2-((2R,4R)-2,4,6-trimethylheptyl)chroman-6-ol.
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Cat. No.: HY-N19234
CAS No.: 74131-93-4
Solanaviol is a spirosolane-type steroidal alkaloid found in the leaves of Solanum aviculare. Alkaloids are a large class of complex nitrogen-containing basic organic compounds. As food, nutritional supplements, and medicines, alkaloids play an important role in medicine and other fields. Alkaloid compounds exhibit good biological activities in anti-inflammatory, anticancer, analgesic, local anesthetic, neuropharmacological, antibacterial, and antifungal properties .
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