2923738-92-3
Chemical Structure
NusB-IN-1
- CAS No.: 2923738-92-3
- Formula:C21H16N2O3
- Molecular Weight:344.36
IUPAC Name: 4-nitro-2-(((2-(phenylethynyl)phenyl)amino)methyl)phenol
InChIKey: WEFCQZIWGCGFIF-UHFFFAOYSA-N
SMILES: O=[N+](C1=CC(CNC2=C(C=CC=C2)C#CC3=CC=CC=C3)=C(C=C1)O)[O-]
Biological Activity: NusB-IN-1 (Compound 22r) is a potent, orally active bacterial rRNA synthesis inhibitor. NusB-IN-1 shows antimicrobial activity against MRSA and VRSA[1]. NusB-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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NusB-IN-1 | NusB-IN-1 (Compound 22r) is a potent, orally active bacterial rRNA synthesis inhibitor. NusB-IN-1 shows antimicrobial activity against MRSA and VRSA. NusB-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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Keywords
