51372-29-3
Chemical Structure
(22R)-Budesonide
Synonym(s): (22R)-BUD
- CAS No.: 51372-29-3
- Formula:C25H34O6
- Molecular Weight:430.53
IUPAC Name: (6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a-dimethyl-10-propyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one
InChIKey: VOVIALXJUBGFJZ-VXKMTNQYSA-N
SMILES: OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(CC4)=CC(C=C5)=O)C)([H])[C@H](C3)O)([H])C[C@@]1([H])O[C@H](O2)CCC)C)=O
Biological Activity: (22R)-Budesonide ((22R)-BUD) is the (22R)-enantiomer of Budesonide (HY-13580). (22R)-Budesonide is a non-halogenated glucocorticoid with high local anti-inflammatory activity[1].
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(22R)-Budesonide | (22R)-Budesonide ((22R)-BUD) is the (22R)-enantiomer of Budesonide (HY-13580). (22R)-Budesonide is a non-halogenated glucocorticoid with high local anti-inflammatory activity. | |||||||||||||||||||||
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(22R)-Budesonide-d6 | (22R)-Budesonide-d6 (Dexbudesonide-d6) is deuterium labeled (22R)-Budesonide. (22R)-Budesonide ((22R)-BUD) is the (22R)-enantiomer of Budesonide (HY-13580). (22R)-Budesonide is a non-halogenated glucocorticoid with high local anti-inflammatory activity. | |||||||||||||||||||||
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(22R)-Budesonide-d8 | (22R)-Budesonide-d8 ((22R)-BUD-d8) is the deuterium labeled (22R)-Budesonide. (22R)-Budesonide ((22R)-BUD) is the (22R)-enantiomer of Budesonide (HY-13580). (22R)-Budesonide is a non-halogenated glucocorticoid with high local anti-inflammatory activity. | |||||||||||||||||||||
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- [1]. Youming Lu, et al. Simultaneous quantification of 22R and 22S epimers of budesonide in human plasma by ultra-high-performance liquid chromatography-tandem mass spectrometry: application in a stereoselective pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Mar 15:921-922:27-34. [Content Brief]
