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Cat. No.: HY-117580S2

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16α-Hydroxyprednisolone-d₅

(Synonyms: OH-PRED-d₅)

16α-Hydroxyprednisolone-d₅ (OH-PRED-d₅) is the deuterium labeled 16α-Hydroxyprednisolone (HY-117580). 16α-Hydroxyprednisolone (OH-PRED) is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid Budesonide (HY-13580). 16α-Hydroxyprednisolone formation is catalyzed by isoenzymes within the cytochrome P450 3A (CYP3A) subfamily. 16α-Hydroxyprednisolone formation can be inhibited by antibodies targeting the CYP3A subfamily.

For research use only. We do not sell to patients.

Formula: C₂₁H₂₃D₅O₆
Molecular Weight:381.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

16α-Hydroxyprednisolone-d₅ Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
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Biological Activity

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 13951-70-7
Molecular Weight 381.47
Formula C₂₁H₂₃D₅O₆
SMILES

O=C1C=C[C@]2(C)[C@@]3([H])[C@@H](O)C[C@]4(C)[C@](C(C([2H])([2H])O)=O)(O)[C@H](O)C[C@@]4([H])[C@]3([H])CC([2H])([2H])C2=C1[2H]
Synonyms

OH-PRED-d₅
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.