7 Results for "

α-globin

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "α-globin" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-108634
CAS No.: 105219-56-5
Purity:  99.93%
Synonyms: WEB 2086
Apafant (WEB 2086), a chemical probe, is a potent platelet-activating factor (PAF) antagonist, inhibits PAF binding to human PAF receptors with a Ki of 9.9 nM. Apafant increases the gene expression of PAF-r, α-globin, β-globin, decreases the c-myb gene expression. Apafant shows a protective effect on alkyl-PAF-mediated lethalit .
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Cat. No.: HY-P99720A
CAS No.: 1373715-00-4
Synonyms: RAP-536

Target:  

TGF-beta/Smad

Research Areas:  

Metabolic Disease

Luspatercept (mIgG2a) (RAP-536) is a fusion protein, consisting of a modified extracellular domain of human ActRIIB linked to the murine IgG2a Fc domain. Luspatercept (mIgG2a) inhibits Smad2/3 signaling, promotes differentiation of late-stage erythroid precursors and mitigates ineffective erythropoiesis (IE) in murine β-thalassemia. Luspatercept (mIgG2a) reduces anemia, α-globin aggregates, hemolysis, and disease complications of IE such as iron overload, splenomegaly, and bone defects .
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Cat. No.: HY-108634S
CAS No.: 1185101-22-7
Synonyms: WEB 2086-d8
Apafant-d8 is the deuterium labeled Apafant. Apafant (WEB 2086) is a potent platelet-activating factor (PAF) antagonist, inhibits PAF binding to human PAF receptors with a Kiof 9.9 nM. Apafant increases the gene expression of PAF-r, α-globin, β-globin, decreases the c-myb gene expression. Apafant shows a protective effect on alkyl-PAF-mediated lethalit .
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Cat. No.: HY-108634R
CAS No.: 105219-56-5
Synonyms: WEB 2086 (Standard)
Apafant (Standard) is the analytical standard of Apafant (HY-108634). This product is intended for research and analytical applications. Apafant (WEB 2086), a chemical probe, is a potent platelet-activating factor (PAF) antagonist, inhibits PAF binding to human PAF receptors with a Ki of 9.9 nM. Apafant increases the gene expression of PAF-r, α-globin, β-globin, decreases the c-myb gene expression. Apafant shows a protective effect on alkyl-PAF-mediated lethalit .
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Cat. No.: HY-P87961
Synonyms: HBA2, HBA1, Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain

Host:  

Rabbit

Application:  

IHC-P, IHC-F, IF-Tissue, WB, FC, IP

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P81428
Synonyms: HBA1; HBA2; Hemoglobin subunit alpha; Alpha-globin; Hemoglobin alpha chain; Hemopressin

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P81428A
Synonyms: HBA1; HBA2; Hemoglobin subunit alpha; Alpha-globin; Hemoglobin alpha chain; Hemopressin

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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