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Apafant (Synonyms: WEB 2086)

Cat. No.: HY-108634
Handling Instructions

Apafant (WEB 2086), a potent platelet-activating factor (PAF) antagonist, inhibits PAF binding to human PAF receptors with a Ki of 9.9 nM.

For research use only. We do not sell to patients.

Apafant Chemical Structure

Apafant Chemical Structure

CAS No. : 105219-56-5

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Description

Apafant (WEB 2086), a potent platelet-activating factor (PAF) antagonist, inhibits PAF binding to human PAF receptors with a Ki of 9.9 nM[1].

IC50 & Target

Ki: 9.9 nM (Platelet-activating factor)[1]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

455.96

Formula

C₂₂H₂₂ClN₅O₂S

CAS No.

105219-56-5

SMILES

O=C(N1CCOCC1)CCC(S2)=CC3=C2N4C(CN=C3C5=CC=CC=C5Cl)=NN=C4C

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Apafant

Cat. No.: HY-108634