1 Result for "

1083-30-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "1083-30-3" in MCE Product Catalog:

Cat. No.: HY-114508
CAS No.: 1083-30-3
Purity:  99.87%
Synonyms: 3-Phenylpropiophenone; β-Phenylpropiophenone
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Dihydrochalcone (3-Phenylpropiophenone) is a Aβ aggregation inhibitor. Dihydrochalcone destabilizes Aβ17-42 protofibrils by disrupting the β-sheet of β1 region. Dihydrochalcone destabilizes both U-shaped Aβ40/Aβ42 protofibrils and S-shaped Aβ42 protofibrils by binding to the protofibril cavity. Dihydrochalcone is the main component of daemonorops draco tree .
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