Search Result

Results for "

11:0 PC

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Pyruvate Carboxylase (PC) (1) Acetyl-CoA Carboxylase (1) Androgen Receptor (1) Biochemical Assay Reagents (3) Insecticide (1) MMP (1) Parasite (1) Raf (1)
By Research Areas:	Cancer (2) Infection (1) Inflammation/Immunology (1) Metabolic Disease (1)
Oligonucleotides:	Fluorescent Lipids (1)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Oligonucleotides

Targets Recommended: Pyruvate Carboxylase (PC)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W339358

11:0 PC 1,2-Diundecanoyl-sn-glycero-3-phosphocholine	Biochemical Assay Reagents	Others
11:0 PC (1,2-Diundecanoyl-sn-glycero-3-phosphocholine) is a phosphatidylcholine, which plays a role in the folding of intact, functionally competent integral membrane proteins .

HY-178040

Insecticidal agent 26	Acetyl-CoA Carboxylase Pyruvate Carboxylase (PC) Parasite Insecticide	Infection
Insecticidal agent 26 (Compound A11), a spiro insecticidal agent, is a dual-functional inhibitor of pest Acetyl-CoA carboxylase (ACC) and Pyruvate carboxylase (PC). Insecticidal agent 26 has potent insecticidal activity against Sogatella furcifera with a LC₅₀ of 11.0  μg/mL, with significant biosafety to bees. Insecticidal agent 26 can be used for management of white-backed planthoppers (WBPs) .

HY-179861

*BODIPY 505/515 11:0* Lyso PC**	Biochemical Assay Reagents	Metabolic Disease
BODIPY 505/515 11:0 Lyso PC is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.

HY-166989

1-undecanoyl-2-hydroxy-sn-glycero-3-phosphocholine 11:0 Lyso PC	Biochemical Assay Reagents	Others
1-Undecanoyl-sn-glycero-3-phosphocholine is a biochemical assay reagent.

HY-147852

B-Raf IN 7	Raf	Cancer
B-Raf IN 7 (compound 6a) is a potent B-Raf inhibitor, with an IC₅₀ of 110.23 nM. B-Raf IN 7 exhibits antitumor activity against colon carcinoma (HCT-116), mammary gland (MCF-7), hepatocellular carcinoma (HEPG-2), human cervical carcinoma (Hela) and human prostate cancer (PC-3) cells, with IC₅₀ values of 7.50, 9.87, 10.57, 11.63 and 12.83 µM .

HY-403733C

JJ-450	Androgen Receptor	Cancer
JJ-450 is a non-competitive antagonist androgen receptor (AR) that inhibits the transcriptional activity of wild-type AR and mutant AR ^F876L. JJ-450 has an IC₅₀ of approximately 1-10 μM in inhibiting AR transcriptional activity in PC3 cells. It is selective for AR binding and does not compete with androgens for binding to the ligand binding domain (LBD) of AR. JJ-450 inhibits the transcriptional activity of AR and its splice variants (such as AR ^F876L) by inhibiting AR nuclear translocation and promoting the degradation of unliganded AR in the nucleus. JJ-450 can be used in castration-resistant prostate cancer (CRPC) studies that are resistant to Enzalutamide (MDV3100) (HY-70003) .

HY-NP110

Highly purified Type II collagen, from mouse sternal cartilage Mouse Type II collagen, immunization grade	MMP	Inflammation/Immunology
Highly purified Type II collagen, from mouse sternal cartilage (Mouse Type II collagen, immunization grade) is an immune grade collagen derived from mouse sternal cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

Cat. No.	Product Name

HY-L110

Cyclic Peptide Library	97 compounds
Cyclic peptides are polypeptide chains taking cyclic ring structure, which exhibit diverse biological activities, such as antibacterial activity, immunosuppressive activity and anti-tumor activity. Cyclic peptides, with the features of good binding affinity, target selectivity and low toxicity, show great success as therapeutics. Multiple cyclic peptides are currently in clinical use, for examples, gramicidin and tyrocidine with bactericidal activity, cyclosporin A with immunosuppressive activity, and vancomycin with antibacterial activity. Furthermore, cyclic peptides usually have the sufficient size and a balanced conformational flexibility/rigidity for binding to flat protein-protein interaction (PPI) interfaces, which have potential to develop PPI drugs. MCE offers a unique collection of 97 cyclic peptides, all of which have good bioactivities. MCE Cyclic Peptide Library is a powerful tool for drug discovery and PPI inhibitor screening.

Cyclic Peptide Library

97 compounds

Cyclic peptides are polypeptide chains taking cyclic ring structure, which exhibit diverse biological activities, such as antibacterial activity, immunosuppressive activity and anti-tumor activity. Cyclic peptides, with the features of good binding affinity, target selectivity and low toxicity, show great success as therapeutics. Multiple cyclic peptides are currently in clinical use, for examples, gramicidin and tyrocidine with bactericidal activity, cyclosporin A with immunosuppressive activity, and vancomycin with antibacterial activity. Furthermore, cyclic peptides usually have the sufficient size and a balanced conformational flexibility/rigidity for binding to flat protein-protein interaction (PPI) interfaces, which have potential to develop PPI drugs.

MCE offers a unique collection of 97 cyclic peptides, all of which have good bioactivities. MCE Cyclic Peptide Library is a powerful tool for drug discovery and PPI inhibitor screening.

Cat. No.	Product Name	Type

HY-W339358

11:0 PC 1,2-Diundecanoyl-sn-glycero-3-phosphocholine	Biochemical Assay Reagents
11:0 PC (1,2-Diundecanoyl-sn-glycero-3-phosphocholine) is a phosphatidylcholine, which plays a role in the folding of intact, functionally competent integral membrane proteins .

HY-166989

1-undecanoyl-2-hydroxy-sn-glycero-3-phosphocholine 11:0 Lyso PC	Biochemical Assay Reagents
1-Undecanoyl-sn-glycero-3-phosphocholine is a biochemical assay reagent.

HY-NP110

Highly purified Type II collagen, from mouse sternal cartilage Mouse Type II collagen, immunization grade	Biochemical Assay Reagents
Highly purified Type II collagen, from mouse sternal cartilage (Mouse Type II collagen, immunization grade) is an immune grade collagen derived from mouse sternal cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

*BODIPY 505/515 11:0* Lyso PC**		Fluorescent Lipids
BODIPY 505/515 11:0 Lyso PC is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

We use cookies

MedChemExpress values your privacy and your trust is important to us. We use cookies to enhance your website experience. Some cookies are necessary to run the website. Privacy and Cookie Policy

Name
Email *

	Sorry, but the email address you supplied was invalid.