1 Result for "

1227045-76-2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "1227045-76-2" in MCE Product Catalog:

Cat. No.: HY-144707
CAS No.: 1227045-76-2
Purity:  98.82%
Target:  

Apoptosis VEGFR MMP PTEN

Research Areas:  

Cancer

AK-778-XXMU is a potent DNA binding inhibitor 2 (ID2) antagonist with a KD of 129 nM. AK-778-XXMU can inhibit cell migration and invasion of glioma cell lines, induce apoptosis, and exhibits significant cancer-suppressing potency. AK-778-XXMU inhibits the ID2-KDR signaling axis, thereby down-regulating the downstream angiogenic factors (VEGFA) and invasion-related proteins (MMP2/9), and up-regulating the tumor suppressor factor (PTEN). AK-778-XXMU can be used for the study of glioma .
loading...
    loading...