1 Result for "

139256-06-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "139256-06-7" in MCE Product Catalog:

Cat. No.: HY-W508552
CAS No.: 139256-06-7
Target:  

PPAR

Research Areas:  

Metabolic Disease

7-Hydroxy-3-(3-methoxyphenyl)-4H-chromen-4-one is a dual agonist of PPARα and PPARγ, with an EC50 of 23.10 μM for human PPARα and an EC50 of 22.29 μM for human PPARγ. 7-Hydroxy-3-(3-methoxyphenyl)-4H-chromen-4-one regulates the expression of lipid metabolism-related genes via PPARα, and modulates the expression of genes associated with glucose homeostasis and adipogenesis via PPARγ. 7-Hydroxy-3-(3-methoxyphenyl)-4H-chromen-4-one can be used in the research of type 2 diabetes and metabolic syndrome .
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