2 Results for "

1460-57-7

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "1460-57-7" in MCE Product Catalog:

trans-Cyclohexane-1,2-diol
trans-Cyclohexane-1,2-diol
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Cat. No.: HY-W010514
CAS No.: 1460-57-7
Category:  

Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

trans-Cyclohexane-1,2-diol (TCHD) is a transient dilator of the nuclear pore complex (NPC). By interacting with the hydrophobic core (FG nucleoporin) of the NPC, trans-Cyclohexane-1,2-diol can disrupt the NPC structure and reversibly increase the permeability of the nuclear pore, allowing macromolecules larger than 40 kDa (such as plasmid DNA) to enter the cell nucleus by passive diffusion, thereby enhancing the nuclear import efficiency of non-viral vectors. trans-Cyclohexane-1,2-diol can improve the efficiency of in vitro electrotransfection or lipid-mediated gene transfection, especially significantly increasing gene expression in differentiated airway epithelial cells .
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trans-Cyclohexane-1,2-diol (Standard)
trans-Cyclohexane-1,2-diol (Standard)
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Cat. No.: HY-W010514R
CAS No.: 1460-57-7
Category:  

Natural Products Endogenous metabolite

Target:  

Endogenous Metabolite Reference Standards

trans-Cyclohexane-1,2-diol (Standard) is the analytical standard of trans-Cyclohexane-1,2-diol (HY-W010514). This product is intended for research and analytical applications. trans-Cyclohexane-1,2-diol (TCHD) is a transient dilator of the nuclear pore complex (NPC). By interacting with the hydrophobic core (FG nucleoporin) of the NPC, trans-Cyclohexane-1,2-diol can disrupt the NPC structure and reversibly increase the permeability of the nuclear pore, allowing macromolecules larger than 40 kDa (such as plasmid DNA) to enter the cell nucleus by passive diffusion, thereby enhancing the nuclear import efficiency of non-viral vectors. trans-Cyclohexane-1,2-diol can improve the efficiency of in vitro electrotransfection or lipid-mediated gene transfection, especially significantly increasing gene expression in differentiated airway epithelial cells .
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