1 Result for "

1609382-32-2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "1609382-32-2" in MCE Product Catalog:

Cat. No.: HY-167754
CAS No.: 1609382-32-2
Target:  

GPR84

Research Areas:  

Inflammation/Immunology

Resolvin D5 n-3 DPA is a Docosapentaenoic acid (DPA) derived specialized proresolving lipid mediator (SPM). Resolvin D5 n-3 DPA is a GPR101, GPR12, and GPR84 agonist with EC50s of 4.6 pM, 14 pM, and 1.5 pM, respectively. Resolvin D5 n-3 DPA possesses potent pro-resolution and anti-inflammatory actions. Resolvin D5 n-3 DPA reduces cell adhesion onto TNF-α-activated human endothelial monolayers. Resolvin D5 n-3 DPA displays potent leukocyte-directed activities, upregulating the ability of neutrophils and macrophages to phagocytose bacteria. Resolvin D5 n-3 DPA can be used for the study of intestinal inflammation .
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