1 Result for "

1645260-76-9

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1645260-76-9" in MCE Product Catalog:

Cat. No.: HY-19927A
CAS No.: 1645260-76-9
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease Endocrinology

DA-6886 is a 5-Hydroxytryptamine receptor 4 (5-HT4) agonist. DA-6886 induces relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensitive manner. The evaluation of DA-6886 in CHO cells expressing hERG channels reveals that it inhibits hERG channel current with an pIC50 value of 4.3, indicating that the compound is 1000-fold more selective for the 5-HT4 receptor over hERG channels. DA-6886 can be used in the study of constipated irritable bowel syndrome .
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