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1648909-73-2

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1 Results for "1648909-73-2" in MCE Product Catalog:

Cat. No.: HY-100476
CAS No.: 1648909-73-2
Research Areas:  

Cancer

Mutant IDH1-IN-3 (Compound 1) is a selective allosteric inhibitor of mutant isocitrate dehydrogenase 1 (IDH1). Mutant IDH1-IN-3 has an IC50 of 13 nM for R132H IDH1. Mutant IDH1-IN-3 inhibits the production of D-2-hydroxyglutaric acid (2HG) in cells. Mutant IDH1-IN-3 can be used in the study of cancer .
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