2 Results for "

174064-08-5

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "174064-08-5" in MCE Product Catalog:

Cat. No.: HY-B0808A
CAS No.: 174064-08-5
Synonyms: Oxaprozinum potassium; Wy21743 potassium
Target:  

COX NF-κB Akt IKK Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Oxaprozin potassium is an orally active and potent COX inhibitor, with IC50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin potassium also inhibits the activation of NF-κB. Oxaprozin potassium induces cell apoptosis. Oxaprozin potassium shows anti-inflammatory activity. Oxaprozin potassium-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties .
loading...
    loading...
Cat. No.: HY-B0808
CAS No.: 21256-18-8
Synonyms: Oxaprozinum; Wy21743
Target:  

COX NF-κB Akt IKK Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Oxaprozin is an orally active and potent COX inhibitor, with IC50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB. Oxaprozin induces cell apoptosis. Oxaprozin shows anti-inflammatory activity. Oxaprozin-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties .
loading...
    loading...