1 Result for "

21253-58-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "21253-58-7" in MCE Product Catalog:

Cat. No.: HY-W587663
CAS No.: 21253-58-7
Research Areas:  

Infection

4 '-DTMP is a DHFR inhibitor with Ki of 5.1 nM (DHFR WT) and 34.3 nM (DHFR L28R), respectively. 4 '-DTMP carries a polar modification that induces additional local interactions with the enzyme. In particular, the hairpin structure on the M20 ring is related to the internal communication of the DHFR. 4 '-DTMP has potential inhibition of E.coli .
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