1 Result for "

2227279-83-4

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2227279-83-4" in MCE Product Catalog:

Cat. No.: HY-154852
CAS No.: 2227279-83-4
Purity:  98.77%
Target:  

GSK-3 CDK

Research Areas:  

Neurological Disease

GSK-3 inhibitor 4 is an orally active and brain-penetrant inhibitor of GSK-3, CDK2, and CDK5, with IC50 values of 0.56 nM (GSK-3β), 0.45 nM (GSK-3α), 0.47 μM, and 0.68 μM, respectively. GSK-3 inhibitor 4 effectively reduces the phosphorylation level of Tau protein. GSK-3 inhibitor 4 can be used in Alzheimer's disease (AD) studies .
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