1 Result for "

23291-96-5

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "23291-96-5" in MCE Product Catalog:

Cat. No.: HY-N9279
CAS No.: 23291-96-5
Synonyms: Monocrotaline pyrrole; MCTP; 3,8-Didehydromonocrotaline
Dehydromonocrotaline is a mitochondrial respiratory chain complex I NADH oxidase inhibitor, with a IC50 of 62.06 μM and a Ki of 8.1 μM in rats. Dehydromonocrotaline exerts non-competitive inhibitory effects by modifying cysteine thiol groups on complex I, and does not bind to the NADH-binding site. Dehydromonocrotaline dissipates mitochondrial membrane potential and reduces ATP levels. Dehydromonocrotaline can be used in studies related to hepatotoxicity, pulmonary hypertension and liver tumors .
loading...
    loading...