1 Result for "

2479378-44-2

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2479378-44-2" in MCE Product Catalog:

Cat. No.: HY-136260
CAS No.: 2479378-44-2
Purity:  94.44%
Research Areas:  

Cancer

DBCO-PEG4-Ahx-DM1 is a agent-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody agent conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. DBCO-PEG4-Ahx-DM1 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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