1 Result for "

2601665-22-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2601665-22-7" in MCE Product Catalog:

Cat. No.: HY-176253
CAS No.: 2601665-22-7
Target:  

Parasite

Research Areas:  

Infection

Antitrypanosomal agent 26 (Compound 1) is an allosteric trypanosome alternative oxidase (TAO) inhibitor. Antitrypanosomal agent 26 exhibits potent activity against African animal trypanosomes (e.g., Trypanosoma brucei, etc.) with an IC50 value of 1.3 nM for recombinant TAO. Antitrypanosomal agent 26 blocks the mitochondrial electron transport chain of trypanosomes and inhibits glucose-dependent respiration. Antitrypanosomal agent 26 is promising for research of African animal trypanosomiasis, such as bovine trypanosomiasis .
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