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2860554-26-1

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1 Results for "2860554-26-1" in MCE Product Catalog:

Cat. No.: HY-151453
CAS No.: 2860554-26-1
Target:  

Topoisomerase Apoptosis

Research Areas:  

Cancer

Topoisomerase IIα-IN-4 (F2) is a non-intercalative ATP-competitive human DNA topoisomerase II inhibitor with an IC50 value of 3.8 and 10.1 μM for TopoIIα and TopoIIβ, respectively. Topoisomerase IIα-IN-4 shows potent potency in apoptosis induction and cell cycle arrest in HepG2 cells. Topoisomerase IIα-IN-4 exhibits strong antitumor activities against human cancer cell lines, it can be used for the research of cancer .
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