1 Result for "

2894793-37-2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2894793-37-2" in MCE Product Catalog:

Cat. No.: HY-175505
CAS No.: 2894793-37-2
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Dopamine D3 receptor antagonist-3 is a D3 dopamine receptor (D3R)-selective positive allosteric modulator (PAM)-antagonist that can cross the blood-brain barrier. Dopamine D3 receptor antagonist-3 exhibits antagonist activity in the D3R-mediated β-arrestin recruitment assay with an IC50 and a Kd of 2.5 μM and 0.49 μM. amine D3 receptor antagonist-3 is also an antagonist in the D3R-mediated Go-BRET assay with an IC50 of 0.34 μM. Dopamine D3 receptor antagonist-3 can be used for the study of neuropsychiatric disorders, including substance use disorder .
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