1 Result for "

2894823-79-9

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2894823-79-9" in MCE Product Catalog:

Cat. No.: HY-162060
CAS No.: 2894823-79-9
Target:  

HDAC NO Synthase Akt PI3K

Research Areas:  

Cardiovascular Disease

YPX-C-05 is an orally active HDAC inhibitor and vasodilator. YPX-C-05 inhibits HDAC enzymatic activity, increases histone H4 acetylation, activates the PI3K/Akt pathway, promotes Akt and eNOS phosphorylation, enhances eNOS activity, and boosts nitric oxide production. YPX-C-05 increases Tetrahydrobiopterin (HY-107383) levels, restores serum nitric oxide levels, reduces endothelin-1 levels, and improves endothelial function. YPX-C-05 reduces vascular remodeling and exerts antihypertensive effects in hypertensive Mus musculus mice. YPX-C-05 can be used for the research of hypertension .
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