1 Result for "

3046451-89-9

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3046451-89-9" in MCE Product Catalog:

Cat. No.: HY-149080
CAS No.: 3046451-89-9
Target:  

Parasite Necroptosis

연구분야:  

Infection

Antiparasitic agent-16, a pyridine-thiazolidinone, has anti-Trypanosoma cruzi and leishmanicidal activities. Antiparasitic agent-16 has IC50s of 1.0 μM and 0.6 μM against trypomastigote and amastigote forms of T. cruzi. Antiparasitic agent-16 has IC50s of 150.2 μM and 16.75 μM against trypomastigote and amastigote forms of L. amazonensis. Antiparasitic agent-16 induces parasite cell death through necrosis induction. Antiparasitic agent-16 induces morphological changes such as shortening, retraction and curvature of the parasite body and leakage of internal content with T. cruzi trypomastigotes .
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