1 Result for "

3076211-50-9

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3076211-50-9" in MCE Product Catalog:

Cat. No.: HY-186024
CAS No.: 3076211-50-9
Target:  

Ras ERK

Research Areas:  

Cancer

KRAS-IN-51 (Compound 597a) is a KRas G12V inhibitor, with its IC50 for KRas G12V being 2.9 nM; KD values are 17 (at 20°C) and 68 (at 37°C) nM. KRAS-IN-51 inhibits the phosphorylation of pERK. KRAS-IN-51 has anti-proliferative activity against SW620 and MIAPaCa-2. KRAS-IN-51 can be used for research on colorectal cancer and pancreatic cancer .
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