1 Result for "

310456-65-6

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "310456-65-6" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-100431
CAS No.: 310456-65-6
Purity:  98.95%
Target:  

Notch

Research Areas:  

Cancer

IMR-1 is a novel class of Notch inhibitor targeting the transcriptional activation with an IC50 of 26 μM. IMR-1 prevents the recruitment of Mastermind-like 1 (Maml1) to the Notch Ternary Complex (NTC) on chromatin, inhibits Notch target gene transcription and dramatically inhibits tumor growth .
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