3 Results for "

338992-53-3

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "338992-53-3" in MCE Product Catalog:

Cat. No.: HY-10260A
CAS No.: 338992-53-3
Synonyms: ZD6474 trifluoroacetate
Target:  

VEGFR Autophagy Apoptosis

Research Areas:  

Cancer

Vandetanib trifluoroacetate (D6474 trifluoroacetate) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib trifluoroacetate also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM) .
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28
28 Publications Verification
Cat. No.: HY-10260
CAS No.: 443913-73-3
Purity:  99.95%
Synonyms: ZD6474
Vandetanib (D6474) is a potent, orally active, and blood-brain-barrier penetrate inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM) .
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Cat. No.: HY-10260B
CAS No.: 524722-52-9
Synonyms: ZD6474 hydrochloride
Target:  

VEGFR Autophagy Apoptosis

Research Areas:  

Cancer

Vandetanib hydrochloride (D6474 hydrochloride) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib hydrochloride also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM) .
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