1 Result for "

42472-93-5

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "42472-93-5" in MCE Product Catalog:

Cat. No.: HY-W1005059
CAS No.: 42472-93-5
Target:  

Ligands for E3 Ligase

Research Areas:  

Cancer

N-Methylthalidomide is a cereblon ligand derivative that acts as an E3 ubiquitin ligase ligand for the synthesis of PROTAC LLC0424N (HY-185557). LLC0424N serves as a negative control for NSD2 PROTAC degrader LLC0424 (HY-161574), with weak ability to induce NSD2 degradation and low growth inhibitory effect on cancer cells carrying NSD2 mutations .
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