1 Result for "

446031-79-4

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "446031-79-4" in MCE Product Catalog:

Cat. No.: HY-19411
CAS No.: 446031-79-4
Target:  

nAChR

Research Areas:  

Neurological Disease

SSR180711 hydrochloride is an orally active, selective and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. SSR180711 hydrochloride can act on rat α7 n-AChR (Ki=22 nM; IC50=30 nM) and human α7 n-AChR (Ki=14 nM; IC50=18 nM). SSR180711 hydrochloride increases glutamatergic neurotransmission, ACh release and long-term potentiation (LTP) in the hippocampus .
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