1 Result for "

908111-22-8

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "908111-22-8" in MCE Product Catalog:

Cat. No.: HY-111165
CAS No.: 908111-22-8
SNX-7081 is an Hsp90 inhibitor with Ki and IC50 values of 26 nM and 44 nM, respectively. SNX-7081 blocks the nuclear translocation of NF-κB, inhibits the production of pro-inflammatory cytokines, attenuates the ERK/JNK and PDGF signaling pathways, and suppresses LPS (HY-D1056)-induced nitric oxide production. SNX-7081 inhibits DNA repair, induces G2/M cell cycle arrest, and triggers apoptosis via downregulation of MYC/nucleolin and activation of Fas. SNX-7081 can be used in research related to rheumatoid arthritis and cancer .
loading...
    loading...