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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
ABCD
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "ABCD" in MCE Product Catalog:
1
Cat. No.: HY-160004
CAS No.: 1523493-53-9
Target:
PXL770 is an orally active, direct allosteric AMP-activated protein kinase (AMPK) activator. PXL770 decreases C26:0 levels, improves mitochondrial respiration, reduces expression of proinflammatory genes and induces expression of compensatory transporters (ABCD2/3) in ALD fibroblasts/lymphocytes. PXL770 normalizes plasma VLCFA levels, significantly reduces elevated VLCFA levels in brain and spinal cord in Abcd1 KO mice. PXL770 improves glycemia, dyslipidemia, and insulin resistance in ob/ob and high-fat diet (HFD)-fed mice. PXL770 can be used for the study of X-linked adrenoleukodystrophy (ALD), autosomal dominant polycystic kidney disease and nonalcoholic steatohepatitis (NASH) .
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VK-0214 is an agonist of the thyroid β receptor (TRβ). By activating the expression of ABCD2, it can reduce the accumulation of very long-chain fatty acids (VLCFAs) and further alleviate glioblastoma multiforme. VK-0214 has the effect of regulating fatty acid metabolism and can be used in the research of X-linked adrenoleukodystrophy (X-ALD) .
Cat. No.: HY-RS00068
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ABCD1 Human Pre-designed siRNA Set A contains three designed siRNAs for ABCD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00069
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ABCD2 Human Pre-designed siRNA Set A contains three designed siRNAs for ABCD2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00070
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ABCD3 Human Pre-designed siRNA Set A contains three designed siRNAs for ABCD3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00071
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ABCD4 Human Pre-designed siRNA Set A contains three designed siRNAs for ABCD4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17901
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Abcd1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Abcd1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24370
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Abcd1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Abcd1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22365
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Abcd3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Abcd3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22366
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Abcd4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Abcd4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS28889
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Abcd3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Abcd3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS28890
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Abcd4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Abcd4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P86759
Synonyms: ABC42 antibody; ABCD1 antibody; ABCD1_HUMAN antibody; Adrenoleukodystrophy protein antibody; ALD antibody; Aldgh antibody; ALDP antibody; AMN antibody; ATP binding cassette, sub family D (ALD), member 1 antibody; ATP-binding cassette sub-family D member 1 antibody; ABC42 antibody; ABCD1 antibody; ABCD1_HUMAN antibody; Adrenoleukodystrophy protein antibody; ALD antibody; Aldgh antibody; ALDP antibody; AMN antibody; ATP binding cassette, sub family D (ALD), member 1 antibody; ATP-binding cassette sub-family D member 1 antibody; OTTHUMP00000025960 antibody; OTTMUSP00000019283 antibody; RGD1562128 antibody; RP23 373N8.2 antibody; X linked adrenoleukodystrophy (ALD) gene homolog antibody;
Cat. No.: HY-183033
CAS No.: 3093663-15-8
Research Areas:
ABC transporter modulator-2 (Compound I-200) is a ABC transporter expression modulator. ABC transporter modulator-2 upregulates the expression of wild-type ABCC6 with an EC50 of <1 μM. ABC transporter modulator-2 upregulates the expression of wild-type ABCB4 with an EC50 of <1 μM. ABC transporter modulator-2 upregulates the expression of wild-type ABCD2 with an EC50 of <1 μM. ABC transporter modulator-2 upregulates the expression of the ABCA4 P1380L mutant with an EC50 of <1 μM. ABC transporter modulator-2 can be used in the research of diseases associated with ABC transporter dysfunction .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
