1 Result for "

ABT-737-d8

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ABT-737-d8" in MCE Product Catalog:

Cat. No.: HY-50907S
CAS No.: 1217686-68-4
ABT 737-d8 is the deuterium labeled ABT-737. ABT-737, a BH3 mimetic, is a potent Bcl-2, Bcl-xL and Bcl-w inhibitor with EC50s of 30.3 nM, 78.7 nM, and 197.8 nM, respectively. ABT-737 induces the disruption of the BCL-2/BAX complex and BAK-dependent but BIM-independent activation of the intrinsic apoptotic pathway. ABT-737 induces autophagy and has the potential for acute myeloid leukemia (AML) research .
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