81 Results for "

ADH

" in MedChemExpress (MCE) Product Catalog:
Products (81)

81 Results for "ADH" in MCE Product Catalog:

10
10 Cited Publications
Cat. No.: HY-13541
CAS No.: 229971-81-7
Purity:  99.93%
Target:  

Cadherin

Research Areas:  

Cancer

ADH-1, an N-cadherin antagonist, inhibits N-cadherin mediated cell adhesion.
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10
10 Cited Publications
Cat. No.: HY-W539944
CAS No.: 129979-57-3
Synonyms: Arg8-vasopressin acetate; AVP acetate
Research Areas:  

Neurological Disease Cancer

Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1 .
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10
10 Cited Publications
Cat. No.: HY-13541A
CAS No.: 1135237-88-5
Purity:  99.74%
Target:  

Cadherin

Research Areas:  

Cancer

ADH-1 trifluoroacetate is an N-cadherin antagonist, which inhibits N-cadherin mediated cell adhesion.
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7
7 Cited Publications
Cat. No.: HY-B1811
CAS No.: 11000-17-2
Synonyms: Arginine vasopressin; Antidiuretic hormone
Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .
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2
2 Cited Publications
Cat. No.: HY-15701B
CAS No.: 2055362-74-6
Purity:  98.04%
Synonyms: (Z)-LeukADHerin-1 choline
Target:  

Complement System

Research Areas:  

Cancer

ADH-503 ((Z)-Leukadherin-1 choline) is an orally active and allosteric CD11b agonist. ADH-503 leads to the repolarization of tumor-associated macrophages, reduction in the number of tumor-infiltrating immunosuppressive myeloid cells, and enhances dendritic cell responses .
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2
2 Cited Publications
Cat. No.: HY-15701A
CAS No.: 2055362-72-4
Purity:  ≥98.0%
Synonyms: ADH-503 free base
Target:  

Complement System

Research Areas:  

Cancer

(Z)-Leukadherin-1 (ADH-503 free base) is an orally active and allosteric CD11b agonist. (Z)-Leukadherin-1 leads to the repolarization of tumor-associated macrophages, reduction in the number of tumor-infiltrating immunosuppressive myeloid cells, and enhances dendritic cell responses .
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1
1 Cited Publications
Cat. No.: HY-B1229
CAS No.: 541-46-8
Synonyms: 3-Methylbutanamide
Isovaleramide (3-Methylbutanamide) is an orally active anticonvulsant. Isovaleramide inhibits alcohol dehydrogenase (ADH) activity and regulates GABAergic system. Isovaleramide reduces acute kidney injury. Isovaleramide has antiepileptic, anxiolytic, sedative and hypnotic effects[1] .
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Cat. No.: HY-N4067
CAS No.: 566-24-5
Synonyms: isoCDCA
Category:  

Natural Products

Isochenodeoxycholic acid (isoCDCA) is a FXR agonist. Isochenodeoxycholic acid activates the activity of FXR and induces the mRNA expression of FXR target genes (Ostβ and Kng1). Isochenodeoxycholic acid serves as a substrate for the liver class I ADH γγ isozyme-mediated 3β-dehydrogenation reaction .
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Cat. No.: HY-118980
CAS No.: 300551-49-9
Purity:  98.70%
Research Areas:  

Metabolic Disease

Sorbitol dehydrogenase-IN-1 is a potent and orally active sorbitol dehydrogenase inhibitor with IC50 s of 4, 5 nM for rat and human, respectively. Sorbitol Dehydrogenase (SDH) is an enzyme that belongs to the zinc-containing alcohol dehydrogenase (ADH) family. ADH and ALDH are enzymes that work together to metabolize alcohol .
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Cat. No.: HY-145785A
CAS No.: 2990065-87-5
Purity:  99.67%
Target:  

MDM-2/p53 Apoptosis

Research Areas:  

Cancer

ADH-6 TFA is a tripyridylamide compound. ADH-6 abrogates self-assembly of the aggregation-nucleating subdomain of mutant p53 DBD. ADH-6 TFA targets and dissociates mutant p53 aggregates in human cancer cells, which restores p53's transcriptional activity, leading to cell cycle arrest and apoptosis. ADH-6 TFA has the potential for the research of cancer diseases .
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Cat. No.: HY-177303
CAS No.: 717104-43-3
Target:  

CaSR SARS-CoV

AXT-914 is a Calcium-sensing receptor (CaSR) inhibitor. AXT-914 has antiviral activity against the coronavirus HCoV 229E and SARS-CoV2. AXT914 reduces cytosolic calcium signalling activity of CaSR mutations. AXT-914 can be used for Bartter syndrome type 5 and autosomal dominant hypocalcemia (ADH) and coronavirus infections research .
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Cat. No.: HY-164690A
CAS No.: 2600354-60-5
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Nicotinamide-guanine dinucleotide sodium, a NAD sodium (HY-B0445A) analog, is an oxidized forms of nicotinamide guanine dinucleotide. Nicotinamide-guanine dinucleotide sodium serves as coenzymes for alcohol dehydrogenase (ADH) in vitro .
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Cat. No.: HY-N1177
CAS No.: 514-07-8
Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC50 values of 512.42 and 500.16 μM, respectively .
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Cat. No.: HY-P0049A
CAS No.: 75499-44-4
Synonyms: Arg8-vasopressin diacetate; AVP diacetate; ADH
Research Areas:  

Neurological Disease Cancer

Argipressin (diacetate) (AVP (diacetate), also known as antidiuretic hormone (ADH)) is a 9 amino acid neuropeptide secreted by the posterior pituitary. Argipressin (diacetate) (AVP (diacetate)) can regulate the biological effects of fluid balance, osmolality and cardiovascular through three separate G-protein coupled receptors (GPCRs), namely Avpr1a (V1a), Avpr1b (V1b) and Avpr2 (V2). Argipressin (diacetate) (AVP (diacetate)) also have potentially important effects on centrally regulated metabolic processes .
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Cat. No.: HY-145785
CAS No.: 2227429-65-2
Target:  

MDM-2/p53 Apoptosis

Research Areas:  

Cancer

ADH-6 is a tripyridylamide compound. ADH-6 abrogates self-assembly of the aggregation-nucleating subdomain of mutant p53 DBD. ADH-6 targets and dissociates mutant p53 aggregates in human cancer cells, which restores p53's transcriptional activity, leading to cell cycle arrest and apoptosis. ADH-6 has the potential for the research of cancer diseases[1].
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Cat. No.: HY-RS00370
Research Areas:  

Others

ADH5 Human Pre-designed siRNA Set A contains three designed siRNAs for ADH5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-122297A
Target:  

Peptides

Research Areas:  

Others

H-​Arg-​Phe-​OH TFA is an amphipathic peptide. H-​Arg-​Phe-​OH TFA has the ability to induce native-like protein aggregation. H-​Arg-​Phe-​OH TFA can induce aggregation of the neutral model protein yeast alcohol dehydrogenase (ADH) .
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Cat. No.: HY-33914
CAS No.: 25222-43-9
4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole (HY-B0876) produced through hepatic oxidative metabolism. 4-Hydroxymethylpyrazole exhibits a plasma concentration that is positively correlated with the administered dosage of Fomepizole, and it demonstrates a relatively short half-life. 4-Hydroxymethylpyrazole demonstrates inhibitory effects on alcohol dehydrogenase (ADH) in both humans and monkeys, but its inhibition constant is significantly higher than that of Fomepizole, rendering its in vivo impact negligible .
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Cat. No.: HY-169025
CAS No.: 2711712-81-9
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

ADH-353 can inhibit Aβ fibrillation and reduce Aβ-induced cytotoxicity in SH-SY5Y and N2a cells. ADH-353 can be used in Alzheimer's disease-related research .
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Cat. No.: HY-RS00369
Research Areas:  

Others

ADH4 Human Pre-designed siRNA Set A contains three designed siRNAs for ADH4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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