300551-49-9
Chemical Structure
Sorbitol dehydrogenase-IN-1
- CAS No.: 300551-49-9
- Formula:C17H25N7O
- Molecular Weight:343.43
IUPAC Name: (R)-1-(4-((2R,6S)-4-(4,6-dimethyl-1,3,5-triazin-2-yl)-2,6-dimethylpiperazin-1-yl)pyrimidin-2-yl)ethan-1-ol
InChIKey: FTEQMUXMWCGJAF-GRYCIOLGSA-N
SMILES: O[C@@H](C1=NC(N2[C@H](C)CN(C[C@@H]2C)C3=NC(C)=NC(C)=N3)=CC=N1)C
Biological Activity: Sorbitol dehydrogenase-IN-1 is a potent and orally active sorbitol dehydrogenase inhibitor with IC50 s of 4, 5 nM for rat and human, respectively. Sorbitol Dehydrogenase (SDH) is an enzyme that belongs to the zinc-containing alcohol dehydrogenase (ADH) family. ADH and ALDH are enzymes that work together to metabolize alcohol[1].
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Sorbitol dehydrogenase-IN-1 | 98.70% | Sorbitol dehydrogenase-IN-1 is a potent and orally active sorbitol dehydrogenase inhibitor with IC50 s of 4, 5 nM for rat and human, respectively. Sorbitol Dehydrogenase (SDH) is an enzyme that belongs to the zinc-containing alcohol dehydrogenase (ADH) family. ADH and ALDH are enzymes that work together to metabolize alcohol. | ||||||||||||||||||||
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