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Sorbitol dehydrogenase-IN-1 

Cat. No.: HY-118980
Handling Instructions

Sorbitol dehydrogenase-IN-1 is a potent and orally active sorbitol dehydrogenase inhibitor with IC50 s of 4, 5 nM for rat and human, respectively.

For research use only. We do not sell to patients.

Sorbitol dehydrogenase-IN-1 Chemical Structure

Sorbitol dehydrogenase-IN-1 Chemical Structure

CAS No. : 300551-49-9

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  • Biological Activity

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Sorbitol dehydrogenase-IN-1 is a potent and orally active sorbitol dehydrogenase inhibitor with IC50 s of 4, 5 nM for rat and human, respectively[1].

IC50 & Target

Sorbitol Dehydrogenase[1]

In Vivo

Sorbitol dehydrogenase-IN-1 (compound 16) (50 µg/kg; p.o.) shows sustained inhibition of sciatic nerve fructose in chronically diabetic rats[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight





C[[email protected]@H]1N(C2=NC([[email protected]](O)C)=NC=C2)[[email protected]@H](CN(C3=NC(C)=NC(C)=N3)C1)C


Room temperature in continental US; may vary elsewhere.


Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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