2055362-74-6
Chemical Structure
ADH-503
Synonym(s): (Z)-Leukadherin-1 choline
- CAS No.: 2055362-74-6
- Formula:C27H28N2O5S2
- Molecular Weight:524.65
IUPAC Name: 2-hydroxy-N,N,N-trimethylethan-1-aminium (Z)-4-(5-((3-benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoate
InChIKey: GOWDQYRMBCOOJR-JHMJKTBASA-M
SMILES: O=C([O-])C1=CC=C(C2=CC=C(/C=C(SC(N3CC4=CC=CC=C4)=S)/C3=O)O2)C=C1.OCC[N+](C)(C)C
Biological Activity: ADH-503 ((Z)-Leukadherin-1 choline) is an orally active and allosteric CD11b agonist. ADH-503 leads to the repolarization of tumor-associated macrophages, reduction in the number of tumor-infiltrating immunosuppressive myeloid cells, and enhances dendritic cell responses[1].
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ADH-503 | 98.04% | ADH-503 ((Z)-Leukadherin-1 choline) is an orally active and allosteric CD11b agonist. ADH-503 leads to the repolarization of tumor-associated macrophages, reduction in the number of tumor-infiltrating immunosuppressive myeloid cells, and enhances dendritic cell responses. | ||||||||||||||||||||
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Keywords
