Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
AP5 sodium
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "AP5 sodium" in MCE Product Catalog:
Cat. No.: HY-112603A
CAS No.: 1623143-67-8
Target:
Research Areas:
AP5 sodium is a potent, orall active, and selective GPR40 receptor agonist with a positive allosteric modulation of endogenous ligand (AgoPAM). AP5 sodium demonstrates rat and human inositol monophosphate (IP1) EC50 values of 0.49 nM and 0.8 nM against the GPR40 receptor, respectively. AP5 sodium has the potential for type II diabetes research .
36
36 Publications Verification
Synonyms: D-APV; D-2-Amino-5-phosphonovaleric acid
Target:
Research Areas:
D-AP5 (D-APV) is a selective and competitive NMDA receptor antagonist with a Kd of 1.4 μM. D-AP5 (D-APV) inhibits the glutamate binding site of NMDA receptors .
3
3 Cited Publications
Synonyms: 2-APV; DL-2-Amino-5-phosphonovaleric acid
Target:
Research Areas:
DL-AP5 (2-APV) is a competitive NMDA (N-methyl-D-aspartate) receptor antagonist. DL-AP5 shows significantly antinociceptive activity. DL-AP5 specifically blocks on channels in the rabbit retina .
3
3 Cited Publications
Synonyms: 2-APV sodium; DL-2-Amino-5-phosphonovaleric acid sodium
Target:
Research Areas:
DL-AP5 (2-APV) sodium is a competitive NMDA (N-methyl-D-aspartate) receptor antagonist. DL-AP5 sodium shows significantly antinociceptive activity. DL-AP5 sodium specifically blocks on channels in the rabbit retina .
Synonyms: AP5A pentasodium; P1,P5-Di(adenosine-5'-)pentAPhosphate pentasodium
Target:
Research Areas:
Diadenosine pentaphosphate (Ap5A; P1,P5-Di(adenosine-5'-)pentaphosphate) pentasodium is an endogenous generated diadenosine polyphosphate, possessing the dual identities of intracellular alarm signal and extracellular signaling molecule. Diadenosine pentaphosphate regulates calcium signaling in the nervous, cardiac and peripheral sensory systems by activating P2X1/P2X3/P2Y receptor and RyR2 channels (EC50 = 140 μM). Diadenosine pentaphosphate can be used in studies related to intracellular calcium release channels, cardiovascular diseases and nociception (pain) .
Cat. No.: HY-112603
CAS No.: 1623194-37-5
Target:
Research Areas:
AP5 is a potent, orlly active, and selective GPR40 receptor agonist with a positive allosteric modulation of endogenous ligand (AgoPAM). AP5 demonstrates rat and human inositol monophosphate (IP1) EC50 values of 0.49 nM and 0.8 nM against the GPR40 receptor, respectively. AP5 has the potential for type II diabetes research .
Cat. No.: HY-100714CR
CAS No.: 1303993-72-7
Synonyms: 2-APV sodium (Standard); DL-2-Amino-5-phosphonovaleric acid sodium (Standard)
Target:
Research Areas:
DL-AP5 (sodium) (Standard) is the analytical standard of DL-AP5 (sodium). This product is intended for research and analytical applications. DL-AP5 (2-APV) sodium is a competitive NMDA (N-methyl-D-aspartate) receptor antagonist. DL-AP5 sodium shows significantly antinociceptive activity. DL-AP5 sodium specifically blocks on channels in the rabbit retina .
Cat. No.: HY-100714R
CAS No.: 76326-31-3
Synonyms: 2-APV (Standard); DL-2-Amino-5-phosphonovaleric acid (Standard)
Target:
Research Areas:
DL-AP5 (Standard) is the analytical standard of DL-AP5. This product is intended for research and analytical applications. DL-AP5 (2-APV) is a competitive NMDA (N-methyl-D-aspartate) receptor antagonist. DL-AP5 shows significantly antinociceptive activity. DL-AP5 specifically blocks on channels in the rabbit retina .
Cat. No.: HY-100714B
CAS No.: 79055-67-7
Synonyms: L-APV; L-2-Amino-5-phosphonovaleric acid
Target:
Research Areas:
L-AP5 (L-APV; L-2-Amino-5-phosphonovaleric acid) is an NMDA antagonist and is the isomer of D-AP5 (HY-100714A).
L-AP5 shows a relatively weak amino acid and synaptic blocking activity .
Cat. No.: HY-100714D
CAS No.: 125229-62-1
Synonyms: 2-APV lithium; DL-2-Amino-5-phosphonovaleric acid lithium
Target:
Research Areas:
DL-AP5 (2-APV) lithium is a competitive NMDA (N-methyl-D-aspartate) receptor antagonist. DL-AP5 lithium shows significantly antinociceptive activity. DL-AP5 lithium specifically blocks on channels in the rabbit retina .
Cat. No.: HY-113273
CAS No.: 41708-91-2
Synonyms: AP5A; P1,P5-Di(adenosine-5'-)pentAPhosphate
Diadenosine pentaphosphate (Ap5A; P1,P5-Di(adenosine-5'-)pentaphosphate) is an endogenous generated diadenosine polyphosphate, possessing the dual identities of intracellular alarm signal and extracellular signaling molecule. Diadenosine pentaphosphate regulates calcium signaling in the nervous, cardiac and peripheral sensory systems by activating P2X1/P2X3/P2Y receptor and RyR2 channels (EC50 = 140 μM). Diadenosine pentaphosphate can be used in studies related to intracellular calcium release channels, cardiovascular diseases and nociception (pain) .
Cat. No.: HY-177023
CAS No.: 103137-88-8
Target:
Research Areas:
Ap5dT is a cytosolic thymidine kinase and mitochondrial enzyme inhibitor with Kis of 0.12 μM and 0.50 μM, respectively. Ap5dT can be used for the study of acute myelocytic leukemia .
Cat. No.: HY-100714AR
CAS No.: 79055-68-8
Synonyms: D-APV (Standard); D-2-Amino-5-phosphonovaleric acid (Standard)
Target:
Research Areas:
D-AP5 (Standard) is the analytical standard of D-AP5 (HY-100714A). This product is intended for research and analytical applications. D-AP5 (D-APV) is a selective and competitive NMDA receptor antagonist with a Kd of 1.4 μM. D-AP5 (D-APV) inhibits the glutamate binding site of NMDA receptors .
Synonyms: AP5A pentaammonium; P1,P5-Di(adenosine-5'-)pentAPhosphate pentaammonium
Target:
Diadenosine pentaphosphate (Ap5A; P1,P5-Di(adenosine-5'-)pentaphosphate) pentaammonium is an endogenous generated diadenosine polyphosphate, possessing the dual identities of intracellular alarm signal and extracellular signaling molecule. Diadenosine pentaphosphate regulates calcium signaling in the nervous, cardiac and peripheral sensory systems by activating P2X1/P2X3/P2Y receptor and RyR2 channels (EC50 = 140 μM). Diadenosine pentaphosphate can be used in studies related to intracellular calcium release channels, cardiovascular diseases and nociception (pain) .
Cat. No.: HY-113273C
CAS No.: 94108-02-8
Synonyms: AP5A pentalithium; P1,P5-Di(adenosine-5'-)pentAPhosphate pentalithium
Target:
Diadenosine pentaphosphate (Ap5A; P1,P5-Di(adenosine-5'-)pentaphosphate) pentalithium is an endogenous generated diadenosine polyphosphate, possessing the dual identities of intracellular alarm signal and extracellular signaling molecule. Diadenosine pentaphosphate regulates calcium signaling in the nervous, cardiac and peripheral sensory systems by activating P2X1/P2X3/P2Y receptor and RyR2 channels (EC50 = 140 μM). Diadenosine pentaphosphate can be used in studies related to intracellular calcium release channels, cardiovascular diseases and nociception (pain) .
Cat. No.: HY-RS00800
Target:
Research Areas:
AP5Z1 Human Pre-designed siRNA Set A contains three designed siRNAs for AP5Z1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RI01653
hsa-miR-548ap-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
