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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
AVAC
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "AVAC" in MCE Product Catalog:
5
Target:
Forschungsgebiete:
Avacopan (CCX168) is a potent, selective and orally available complement 5a receptor (C5aR) inhibitor with an IC50 of 0.1 nM.
Synonyms: ARC1905
Target:
Forschungsgebiete:
Avacincaptad pegol (ARC1905) sodium is a 40KDa PEG-conjugated aptamer. Avacincaptad pegol sodium targets complement factor 5 (C5), inhibits the cleavage of C5 into C5a and C5b, limits inflammatory stimulation and complement membrane attack complex (MAC), and is used to study age-related macular degeneration (AMD). Avacincaptad pegol sodium limits irregular cell apoptosis by targeting downstream factors in the complement cascade while preserving the early steps of the complement system .
Art. -Nr.: HY-148457
CAS. Nr.: 1613641-69-2
Synonyms: Izervay
Target:
Forschungsgebiete:
Avacincaptad pegol (Izervay) is a selective inhibitor targeting complement component C5, and is a pegylated ribonucleic acid aptamer. Avacincaptad pegol inhibits the cleavage of C5 into pro-inflammatory C5a and C5b, which forms the membrane attack complex (C5b-9), thereby reducing inflammatory cell recruitment and retinal cell damage. Avacincaptad pegol can slow the growth of geographic atrophy (GA) lesions and reduce the risk of persistent vision loss. Avacincaptad pegol can be used in research of geographic atrophy associated with age-related macular degeneration (AMD) and has been approved by the FDA .
Art. -Nr.: HY-17627R
CAS. Nr.: 1346623-17-3
Synonyms: CCX168 (Standard)
Target:
Forschungsgebiete:
Avacopan (Standard) is the analytical standard of Avacopan. This product is intended for research and analytical applications. Avacopan (CCX168) is a potent, selective and orally available complement 5a receptor (C5aR) inhibitor with an IC50 of 0.1 nM.
Art. -Nr.: HY-17627S1
CAS. Nr.: 2316781-85-6
Synonyms: CCX168-d4
Art. -Nr.: HY-147080C
Target:
Forschungsgebiete:
FAM labled Avacincaptad pegol sodiumis a FAM labled Avacincaptad pegol sodium.
Art. -Nr.: HY-147080D
Target:
Forschungsgebiete:
Cy3 labled Avacincaptad pegol sodium is a Cy3 labled Avacincaptad pegol sodium.
Art. -Nr.: HY-147080B
Target:
Forschungsgebiete:
Avacincaptad pegol sodium scrambled negative control is the sequence scrambled negative control of Avacincaptad pegol sodium.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
