1 Result for "

AZ10397767

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AZ10397767" in MCE Product Catalog:

Cat. No.: HY-124056
CAS No.: 333742-63-5
Target:  

CXCR

Research Areas:  

Cancer

AZ10397767 is an orally active, selective CXCR2 receptor antagonist with an IC50 of 1 nM. AZ10397767 attenuates the Oxaliplatin (HY-17371)-induced NF-κB transcriptional activity and potentiates Oxaliplatin-induced apoptosis in androgen-independent prostate cancer (AIPC) cells. AZ10397767 significantly inhibits neutrophil recruitment into tumors which then adversely affects tumor growth in vitro and in vivo .
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