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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
Angiotensinogen
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "Angiotensinogen" in MCE Product Catalog:
Cat. No.: HY-P1486
CAS No.: 104180-23-6
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Cat. No.: HY-P1839A
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Cat. No.: HY-75992
CAS No.: 74007-20-8
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Cardiovascular Disease Metabolic Disease Inflammation/Immunology Endocrinology
trans-Doxercalciferol is an isomer of Doxercalciferol (HY-32348). Doxercalciferol is a vitamin D receptor agonist. Doxercalciferol reduces proteinuria, podocyte injury, mesangial expansion, extracellular matrix accumulation, macrophage infiltration, oxidative stress, proinflammatory cytokines, profibrotic growth factors, renal neutral lipid accumulation, albuminuria and glomerulosclerosis. Doxercalciferol alleviates high-salt diet-induced myocardial hypertrophy. trans-Doxercalciferol is used for the research of diet-induced obesity-related nephropathy, diabetic nephropathy, myocardial hypertrophy, cardiac dysfunction and secondary hyperparathyroidism .
Cat. No.: HY-147406
CAS No.: 2589926-20-3
Synonyms: ION-904
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Cat. No.: HY-P5939
CAS No.: 82048-97-3
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Cat. No.: HY-P5123A
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Cat. No.: HY-P1829A
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Cat. No.: HY-145649
CAS No.: 2380166-33-4
Synonyms: AD-85481; ALN-AGT
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Zilebesiran is a siRNA that reduce hepatic angiotensinogen levels through RNA interference. it is used for the study of mild to moderate Hypertension. Angiotensinogen is the predominant precursor of angiotensin peptides and a key regulator of systemic blood pressure.
Cat. No.: HY-P1829
CAS No.: 47896-63-9
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Cat. No.: HY-147267
CAS No.: 2589926-22-5
Synonyms: ISIS-757456
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Evazarsen is an angiotensinogen synthesis inhibitor and possesses antihypertensive properties .
Cat. No.: HY-P2686
CAS No.: 66641-26-7
Cat. No.: HY-P1486A
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Cat. No.: HY-145649A
CAS No.: 2380166-34-5
Synonyms: AD-85481 sodium; ALN-AGT sodium
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Zilebesiran (AD-85481; ALN-AGT) sodium is a long-acting liver-targeted small interfering RNA (siRNA) antihypertensive agent. Zilebesiran sodium binds to the hepatic asialoglycoprotein receptor (ASGPR), activates the RNA-induced silencing complex to degrade hepatic angiotensinogen mRNA, thereby inhibiting the gene expression and synthesis of angiotensinogen. Zilebesiran sodium dose-dependently reduces serum angiotensinogen levels and 24-hour ambulatory blood pressure, with its effect persisting throughout the circadian cycle. Zilebesiran sodium is applicable to research related to hypertension .
Cat. No.: HY-P1839
CAS No.: 58442-64-1
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Cat. No.: HY-P10181
CAS No.: 104180-27-0
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Cat. No.: HY-P5385
CAS No.: 110200-37-8
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Cat. No.: HY-147267A
CAS No.: 2589926-24-7
Synonyms: ISIS-757456 sodium
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Evazarsen sodium is an angiotensinogen synthesis inhibitor and possesses antihypertensive properties .
Cat. No.: HY-147406A
CAS No.: 2589926-21-4
Synonyms: ION-904 sodium
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Cat. No.: HY-P2492
CAS No.: 142988-22-5
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Cat. No.: HY-P5123
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
