2589926-20-3
2589926-20-3
Chemical Structure
Tonlamarsen
Synonym(s): ION-904
- CAS No.: 2589926-20-3
- Formula:C241H349N65O12P16S12
- Molecular Weight:7021.13
IUPAC Name: hydrazine-15N2 sulfate
SMILES: [Tonlamarsen]
Biological Activity: Tonlamarsen (ION-904) is a GalNAc-conjugated antisense oligonucleotide and Angiotensinogen synthesis inhibitor. Tonlamarsen specifically reduces the production of Angiotensinogen in the liver and plasma, and exhibits extremely low activity in the kidneys. Tonlamarsen can be used in research related to hypertension and heart failure[1].
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Tonlamarsen | Tonlamarsen (ION-904) is a GalNAc-conjugated antisense oligonucleotide and Angiotensinogen synthesis inhibitor. Tonlamarsen specifically reduces the production of Angiotensinogen in the liver and plasma, and exhibits extremely low activity in the kidneys. Tonlamarsen can be used in research related to hypertension and heart failure. | |||||||||||||||||||||
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References
Keywords
