2 Results for "

BGB16673

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "BGB16673" in MCE Product Catalog:

Cat. No.: HY-160141
CAS No.: 2736508-60-2
Synonyms: BGB-16673; BTK-IN-29
Target:  

PROTACs Btk NF-κB

Research Areas:  

Inflammation/Immunology Cancer

BGB-16673 (BGB-16673) is an orally active, selective BTK PROTAC degrader (IC50=0.69 nM). BGB-16673 ligates BTK to E3 ubiquitin ligase, causing BTK to undergo polyubiquitination, which is then recognized and degraded by the proteasome, thereby exerting efficient BTK degradation activity. BGB-16673 can be used in the research of B-cell malignancies such as chronic lymphocytic leukemia, small lymphocytic lymphoma, and mantle cell lymphoma .
loading...
    loading...
Cat. No.: HY-148026
CAS No.: 2383086-06-2
Purity:  99.61%
Synonyms: BGB 11417
Target:  

Bcl-2 Family

Research Areas:  

Cancer

Sonrotoclax is a potent, orally active Bcl2 inhibitor. Sonrotoclax has effective cell killing effect against a variety of lymphoma and leukemia cell lines .
loading...
    loading...