1. Search Result
Search Result
Results for "

BS

" in MedChemExpress (MCE) Product Catalog:

64

Inhibitors & Agonists

2

Fluorescent Dyes

3

Biochemical Assay Reagents

1

Peptides

8

Natural
Products

4

Recombinant Proteins

8

Isotope-Labeled Compounds

4

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10095
    Olcegepant
    Maximum Cited Publications
    42 Publications Verification

    BIBN-4096; BIBN 4096BS

    CGRP Receptor Neurological Disease
    Olcegepant (BIBN-4096) is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and Ki of 14.4 pM for human CGRP .
    Olcegepant
  • HY-124329
    BS3 Crosslinker
    1 Publications Verification

    Biochemical Assay Reagents Cancer
    BS3 Crosslinker is an amine-reactive homobifunctional protein crosslinker. BS3 Crosslinker enables stable protein-protein, peptide, and biomolecule conjugation.
    BS3 Crosslinker
  • HY-124329A
    BS3 Crosslinker disodium
    1 Publications Verification

    Biochemical Assay Reagents Cancer
    BS3 Crosslinker disodium is an amine-reactive homobifunctional protein crosslinker. BS3 Crosslinker disodium enables stable protein-protein, peptide, and biomolecule conjugation.
    BS3 Crosslinker disodium
  • HY-A0095
    Flibanserin
    2 Publications Verification

    BIMT-17; BIMT-17BS

    5-HT Receptor Neurological Disease Cancer
    Flibanserin (BIMT-17; BIMT-17BS) is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research - .
    Flibanserin
  • HY-145583

    Hemay005

    Phosphodiesterase (PDE) Others Inflammation/Immunology
    Mufemilast (Heymay005) is a selective and orally active phosphodiesterase 4 (PDE4) inhibitor (IC50 = 80-120 nM). Mufemilast modulates cytokines upregulated in Behςet’s syndrome (BS). Mufemilast displays a significant inhibitory effect on TNF-α, which is an important proinflammatory cytokine target in the disease process of psoriasis. Mufemilast can be studied in research for diseases such as rheumatoid arthritis, psoriasis and BS .
    Mufemilast
  • HY-10095A
    Olcegepant hydrochloride
    Maximum Cited Publications
    42 Publications Verification

    BIBN-4096 hydrochloride; BIBN4096BS hydrochloride

    CGRP Receptor Neurological Disease
    Olcegepant hydrochloride (BIBN-4096 hydrochloride) is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and with a Ki of 14.4 pM for human CGRP .
    Olcegepant hydrochloride
  • HY-146331

    Bacterial Infection
    PC190723 is a bacterial cell division protein FtsZ inhibitor (IC50 = 55 nM). PC 190723 prevents cell division. PC190723 has potent and selective bactericidal activity against staphylococci, including methicillin- and multi-drug-resistant Staphylococcus aureus. PC190723 induces nucleated assembly of Bs-FtsZ into single-stranded coiled protofilaments and polymorphic condensates. PC190723 can be studied in anti-bacterial infection research .
    PC190723
  • HY-12489A

    Acid Red 112, BS

    Biochemical Assay Reagents Others
    Both Ponceau S and Ponceau BS are synthetic dyes commonly used in biological research. They are commonly used as protein stains to visualize proteins in western blots and other protein detection analyses. Ponceau S is a red dye, while Ponceau BS is a blue shade of the same dye. Both dyes bind to positively charged amino acid residues in proteins for easy visualization. However, Ponceau S is more commonly used due to its higher sensitivity.
    Ponceau S, BS
  • HY-13266A
    BS-181 hydrochloride
    5+ Cited Publications

    CDK Cancer
    BS-181 hydrochloride is a highly selective CDK7 inhibitor with IC50 of 21 nM, and > 40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9.
    BS-181 hydrochloride
  • HY-14372

    CDK Cancer
    BS-194 is an orally active, selective and potent CDK inhibitor. BS-194 inhibits CDK2, CDK1, CDK5, CDK7, CDK9 (IC50s: 3, 30, 30, 250, and 90 nM respectively). BS-194 potently inhibits cancer cells proliferation. BS-194 can be used in the research of cancers like breast cancer, colon cancer .
    BS-194
  • HY-W016510

    Biochemical Assay Reagents Drug Intermediate Others
    Benzenesulfonate sodium is the sodium salt of Benzenesulfonic acid. Benzenesulfonate sodium facilitates the identification of -SO3H and -SO3 - vibrational bands in compounds in Raman spectroscopy. Benzenesulfonate sodium was used in the synthesis of 1-Butyl-3-propanenitrile imidazolium benzenesulfonate [C2CN Bim]BS .
    Benzenesulfonate sodium
  • HY-121525

    Ponceau BS

    Biochemical Assay Reagents Others
    Biebrich scarlet is an azo organosulfur dyes.
    Biebrich scarlet
  • HY-13266

    CDK Apoptosis Cancer
    BS-181 is a potent and selective CDK7 inhibitor (IC50=21 nM) than Seliciclib (HY-30237). BS-181 is also against CDK2, CDK5 and CDK9 with IC50 values of 880, 3000 and 4200 nM, respectively (fails to block CDK1, 4 and 6). BS-181 inhibits a panel of cancer cells growth (IC50=11.5 μM-37.3 μM) and induces cell apoptosis. BS-181 has the potential for the research of cancer therapy .
    BS-181
  • HY-A0095A

    BIMT-17 hydrochloride (propan-2-ol) hydrate; BIMT-17BS hydrochloride (propan-2-ol) hydrate

    5-HT Receptor Neurological Disease Cancer
    Flibanserin (BIMT-17) hydrochloride (propan-2-ol) hydrate is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin hydrochloride (propan-2-ol) hydrate binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin hydrochloride (propan-2-ol) hydrate shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research - .
    Flibanserin hydrochloride (propan-2-ol) hydrate
  • HY-B0590D

    (-)-TBZ; (3S,11BS)-TBZ; (3S,11BS)-Tetrabenazine

    Monoamine Transporter Neurological Disease
    (-)-Tetrabenazine ((-)-TBZ; compound 13) is an enantiomer of Tetrabenazine (HY-B0590). (+)-Tetrabenazine proves 3-fold more active than (-)-Tetrabenazine in inhibiting vesicular monoamine transporter 2 (VMAT2) .
    (-)-Tetrabenazine
  • HY-N2203A

    Others Others
    Vitexin2''-O-p-trans-coumarate is a flavonoid, can be isolated from the Et acetate-soluble fraction of the ethanolic extract of the seeds of Trigonella foenum-graecum. Vitexin2''-O-p-trans-coumarate strongly promotes 2BS cell proliferation induced by H2O2 .
    Vitexin2''-O-p-trans-coumarate
  • HY-110368

    CDK Cancer
    BS-181 dihydrochloride is a potent and selective CDK7 inhibitor (IC50=21 nM) than Seliciclib (HY-30237). BS-181 is also against CDK2, CDK5 and CDK9 with IC50 values of 880 nM, 3000 nM and 4200 nM, respectively (fails to block CDK1, 4 and 6). BS-181 dihydrochloride inhibits a panel of cancer cells growth (IC50=11.5 μM-37.3 μM) and induces cell apoptosis. BS-181 dihydrochloride has the potential for the research of cancer therapy .
    BS-181 dihydrochloride
  • HY-121033

    Sigma Receptor p38 MAPK Apoptosis Cancer
    BS148 is a selective sigma-2 receptor (S2R) agonist with a Ki 20 nM. BS148 shows >80-fold selective for S2R than S1R. BS148 activates the endoplasmic reticulum stress response through the upregulation of protein kinase R-like ER kinase (PERK), activating transcription factor 4 (ATF4) genes, and C/EBP homologous protein (CHOP). BS148 induces apoptosis in melanoma cell. BS148 downregulates genes related to the cholesterol pathway and activates the MAPK signaling pathway. BS148 can be used for the study of melanoma .
    BS148
  • HY-W150426

    CMV DNA/RNA Synthesis Infection
    Naphthol AS-BS (Compound 1) is a human cytomegalovirus (HCMV) DNA polymerase alpha inhibitor with an IC50 of 12 μM. Naphthol AS-BS can be used for the research of infection .
    Naphthol AS-BS
  • HY-130547A

    DNA Alkylator/Crosslinker Cancer
    BS2G Crosslinker is an amine-reactive homobifunctional protein crosslinker. BS2G Crosslinker enables stable protein-protein, peptide, and biomolecule conjugation.
    BS2G Crosslinker
  • HY-130547

    DNA Alkylator/Crosslinker Cancer
    BS2G Crosslinker disodium is an amine-reactive homobifunctional protein crosslinker. BS2G Crosslinker disodium enables stable protein-protein, peptide, and biomolecule conjugation.
    BS2G Crosslinker disodium
  • HY-111878

    SNIPERs Cancer
    BzNH-BS contains two different ligands, methyl-bestatin (MeBS) for cIAP1 and benzoyl-amide, which are connected by linkers. MeBS as a ligand for cellular inhibitor of apoptosis protein 1 (cIAP1) ubiquitin ligase .
    BzNH-BS
  • HY-A0095B

    BIMT-17 hydrochloride; BIMT-17BS hydrochloride

    5-HT Receptor Dopamine Receptor Neurological Disease
    Flibanserin hydrochloride (BIMT-17 hydrochloride) is an orally active 5-HT1A receptor agonist and 5-HT2A receptor antagonist with binding affinities Ki of 1 nM and 49 nM, respectively. Flibanserin hydrochloride also binds to dopamine D4 receptors with a Ki of 4-24 nM. Flibanserin hydrochloride has antidepressant and anxiolytic effects and can be used in the study of hypoactive sexual desire disorder (HSDD) .
    Flibanserin hydrochloride
  • HY-163687

    BS-7723 free base

    Biochemical Assay Reagents Cancer
    Tropirine (BS-7723 free base) is a radiosensitizer. Tropirine can be used in cancer research .
    Tropirine
  • HY-164022

    BS 7573a

    Biochemical Assay Reagents Others
    Acridorex (BS 7573a) is an anorectic agent .
    Acridorex
  • HY-111879

    SNIPERs Cancer
    Biotin-BS contains two different ligands, methyl-bestatin (MeBS) for cIAP1 and biotin, which are connected by linkers. MeBS as a ligand for cellular inhibitor of apoptosis protein 1 (cIAP1) ubiquitin ligase .
    Biotin-BS
  • HY-123360

    BIBW22BS

    Drug Derivative Cancer
    BIBW 22 (BIBW22BS) is a dipyridamole analogue. BIBW 22 is a potent bifunctional modulator that affects p-glycoprotein and nucleoside transport in tumor cells .
    BIBW 22
  • HY-Z2775R

    Reference Standards
    (6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10-trimethyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one (Budesonide Impurity) (Standard) is the analytical standard of (6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10-trimethyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one (Budesonide Impurity). This product is intended for research and analytical applications.
    (6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10-trimethyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one (Budesonide Impurity) (Standard)
  • HY-A0095R

    BIMT-17 (Standard); BIMT-17BS (Standard)

    Reference Standards 5-HT Receptor Neurological Disease Cancer
    Flibanserin (Standard) is the analytical standard of Flibanserin. This product is intended for research and analytical applications. Flibanserin (BIMT-17; BIMT-17BS) is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research - .
    Flibanserin (Standard)
  • HY-W753222

    Bedaquiline fumarate impurity 8-d6

    Isotope-Labeled Compounds Others
    (aS,bS)-rel-Bedaquiline-d6 (Bedaquiline fumarate impurity 8-d6) is the deuterium labeled (1S,2S)-1-(6-Bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol (HY-14881E).
    (aS,bS)-rel-Bedaquiline-d6
  • HY-N14615

    Antibiotic Bacterial Infection
    Pyrisulfoxin A is an antibiotic found in Streptomyces callfornicus BS-75 .
    Pyrisulfoxin A
  • HY-N14951

    Antibiotic Bacterial Infection
    Pyrisulfoxin B is an antibiotic found in Streptomyces callfornicus BS-75 .
    Pyrisulfoxin B
  • HY-N10906

    Others Others
    (4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one is a sesquiterpene lactone .
    (4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one
  • HY-Z8110R

    Reference Standards
    2-Oxo-2-((4aS,4bS,5aS,6aS,7R,8S,9aS,9bS)-4a,6a,8-trimethyl-2-oxo-7-(propionyloxy)-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl)ethyl propionate (Betamethasone Dipropionate Impurity) (Standard) is the analytical standard of 2-Oxo-2-((4aS,4bS,5aS,6aS,7R,8S,9aS,9bS)-4a,6a,8-trimethyl-2-oxo-7-(propionyloxy)-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl)ethyl propionate (Betamethasone Dipropionate Impurity). This product is intended for research and analytical applications.
    Betamethasone dipropionate impurity 3 (Standard)
  • HY-125131

    NO Synthase COX Inflammation/Immunology Cancer
    Buddlejasaponin IV (BS‐IV) exerts anti-inflammatory and cytotoxic effects against cancer cells .
    Buddlejasaponin IV
  • HY-W741425

    Isotope-Labeled Compounds Others
    21-O-Acetyl dexamethasone 9,11-epoxide-d5 is the deuterium labeled 2-((4aS,4bS,5aS,6aS,7R,8R,9aS,9bS)-7-Hydroxy-4a,6a,8-trimethyl-2-oxo-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl)-2-oxoethyl acetate (Dexamethasone Acetate Impurity) (HY-Z8003).
    21-O-Acetyl dexamethasone 9,11-epoxide-d5
  • HY-RS05608

    Small Interfering RNA (siRNA) Others

    GP1BB Human Pre-designed siRNA Set A contains three designed siRNAs for GP1BB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    GP1BB Human Pre-designed siRNA Set A
    GP1BB Human Pre-designed siRNA Set A
  • HY-RS01520

    Small Interfering RNA (siRNA) Others

    BLM Human Pre-designed siRNA Set A contains three designed siRNAs for BLM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    BLM Human Pre-designed siRNA Set A
    BLM Human Pre-designed siRNA Set A
  • HY-105000S1

    Isotope-Labeled Compounds Others
    trans-Dihydro Tetrabenazine-d7 is deuterium labeled (2S,3S,11bS)-3-Isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol.
    trans-Dihydro Tetrabenazine-d7
  • HY-N2203

    Others Others
    Vitexin2''-O-p-coumarate is isolated from fenugreek seeds. Vitexin2''-O-p-coumarate strongly promotes 2BS cell proliferation induced by H2O2 .
    Vitexin2''-O-p-coumarate
  • HY-163882

    Bacterial DNA/RNA Synthesis Infection
    CUHK242 is a bacterial transcription inhibitor, with a MIC of 2 μg/mL for B. subtilis reporter strain BS2019. CUHK242 has antimicrobial activity against Staphylococcus aureus. CUHK242 can inhibit RNA synthesis in cells, thereby simultaneously reducing protein synthesis .
    CUHK242
  • HY-N12164

    Bacterial Fungal Infection
    Linearmycin B is an antibacterial and antifungal agent. Linearmycin B shows activity against Bacillus subtilis (Bs), Staphylococcus aureus (Sa). Candida albicans (Ca), and Saccharomyces cerevisiae (Sc), with MIC values of 0.097, 1.5, 0.0008, and 0.0002 μg/mL, respectively .
    Linearmycin B
  • HY-119022

    Bacterial Infection
    MAC-0547630 is a potent inhibitor of undecaprenyl diphosphate synthase (UppS), with IC50s of 0.05 μM and 1.6 μM for UppS BS and UppS BA, respectively. MAC-0547630 is active against B. subtilis in vitro (MIC 0.1 ng/mL) .
    MAC-0547630
  • HY-A0095AS

    BIMT-17-d4 hydrochloride; BIMT-17BS-d4 hydrochloride

    5-HT Receptor Isotope-Labeled Compounds Others
    Flibanserin-d4 (hydrochloride) is the deuterium labeled Flibanserin hydrochloride .
    Flibanserin-d4 hydrochloride
  • HY-P5790

    Sodium Channel Neurological Disease
    μ-TRTX-Hd1a, a spider venom, is a selective NaV 1.7 inhibitor. μ-TRTX-Hd1a is a gating modifier that inhibits human NaV 1.7 by interacting with the S3b-S4 paddle motif in channel domain II .
    μ-TRTX-Hd1a
  • HY-163523

    Microtubule/Tubulin Cancer
    PYRIB-SO 2 is a potent antimitotic agent. PYRIB-SO 2 shows antiproliferative activity and induces cell cycle arrest at G2/M phase. PYRIB-SO 2 reduces and disruptes microtubule structures. PYRIB-SO 2 binds to the colchicine-binding site (C-BS) of α, β-tubulin .
    PYRIB-SO 2
  • HY-W016510R

    Reference Standards Biochemical Assay Reagents Drug Intermediate Others
    Benzenesulfonate (sodium) (Standard) is an analytical standard for Benzenesulfonate sodium (HY-W016510). This product is intended for research and analytical applications. Benzenesulfonate sodium is the sodium salt of Benzenesulfonic acid. Benzenesulfonate sodium facilitates the identification of -SO3H and -SO3 - vibrational bands in compounds in Raman spectroscopy. Benzenesulfonate sodium was used in the synthesis of 1-Butyl-3-propanenitrile imidazolium benzenesulfonate [C2CN Bim]BS .
    Benzenesulfonate sodium (Standard)
  • HY-RS07320

    Small Interfering RNA (siRNA) Others

    Kit Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kit gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Kit Mouse Pre-designed siRNA Set A
    Kit Mouse Pre-designed siRNA Set A
  • HY-A0095S

    BIMT-17-d4; BIMT-17BS-d4

    5-HT Receptor Neurological Disease
    Flibanserin-d4 is a deuterium labeled Flibanserin (BIMT-17). Flibanserin is a full agonist of the serotonin 5-HT1A receptor (Ki=1 nM) and an antagonist of 5-HT2A (49 nM) .
    Flibanserin-d4
  • HY-A0095S1

    BIMT-17-d4-1; BIMT-17BS-d4-1

    Isotope-Labeled Compounds 5-HT Receptor Neurological Disease
    Flibanserin-d4-1 is deuterium labeled Flibanserin. Flibanserin (BIMT-17) is a full agonist of the serotonin 5-HT1A receptor (Ki=1 nM) and an antagonist of 5-HT2A (49 nM). Flibanserin binds to dopamine D4 receptors (4-24 nM), and has negligible affinity for a variety of other neurotransmitter receptors and ion channels. Flibanserin is efficacious in treating hypoactive sexual desire disorder (HSDD) .
    Flibanserin-d4-1

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

 

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

 

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: