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  4. BS3 Crosslinker

BS3 Crosslinker is an amine-reactive homobifunctional protein crosslinker. BS3 Crosslinker enables stable protein-protein, peptide, and biomolecule conjugation.

For research use only. We do not sell to patients.

CAS No. : 82436-77-9

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of BS3 Crosslinker:

BS3 Crosslinker Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE BS3 Crosslinker

WB

    BS3 Crosslinker purchased from MedChemExpress. Usage Cited in: Int J Oral Sci. 2025 Sep 12;17(1):64.  [Abstract]

    The EGFR dimerization assay of oral cancer cells with or without hypoxia treatment adopted BS3 Crosslinker disodium (BS3) as a cross-linking agent.

    • Biological Activity

    • Purity & Documentation

    • Customer Review

    Description

    BS3 Crosslinker is an amine-reactive homobifunctional protein crosslinker. BS3 Crosslinker enables stable protein-protein, peptide, and biomolecule conjugation.

    Molecular Weight

    528.47

    Formula

    C16H20N2O14S2
    CAS No.
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    O=C(CCCCCCC(ON1C(C(CC1=O)S(=O)(O)=O)=O)=O)ON2C(C(CC2=O)S(=O)(O)=O)=O
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    -20°C, sealed storage, away from moisture

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

    Solvent & Solubility
    In Vitro: 

    DMSO : 175 mg/mL (331.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

    H2O : 100 mg/mL (189.23 mM; Need ultrasonic)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 1.8923 mL 9.4613 mL 18.9226 mL
    5 mM 0.3785 mL 1.8923 mL 3.7845 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

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    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Purity & Documentation

    Purity: 99.84%

    SDS (394 KB)

    COA (246 KB) HNMR (287 KB) RP-HPLC (218 KB) MS (90 KB)

    Handling Instructions (2659 KB)

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O / DMSO 1 mM 1.8923 mL 9.4613 mL 18.9226 mL 47.3064 mL
    5 mM 0.3785 mL 1.8923 mL 3.7845 mL 9.4613 mL
    10 mM 0.1892 mL 0.9461 mL 1.8923 mL 4.7306 mL
    15 mM 0.1262 mL 0.6308 mL 1.2615 mL 3.1538 mL
    20 mM 0.0946 mL 0.4731 mL 0.9461 mL 2.3653 mL
    25 mM 0.0757 mL 0.3785 mL 0.7569 mL 1.8923 mL
    30 mM 0.0631 mL 0.3154 mL 0.6308 mL 1.5769 mL
    40 mM 0.0473 mL 0.2365 mL 0.4731 mL 1.1827 mL
    50 mM 0.0378 mL 0.1892 mL 0.3785 mL 0.9461 mL
    60 mM 0.0315 mL 0.1577 mL 0.3154 mL 0.7884 mL
    80 mM 0.0237 mL 0.1183 mL 0.2365 mL 0.5913 mL
    100 mM 0.0189 mL 0.0946 mL 0.1892 mL 0.4731 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    BS3 Crosslinker Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    BS3 Crosslinker82436-77-9Biochemical Assay ReagentsInhibitorinhibitorinhibit

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    Product Name:
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    Cat. No.:
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