47 Results for "

Benzothiazole

" in MedChemExpress (MCE) Product Catalog:
Products (47)

47 Results for "Benzothiazole" in MCE Product Catalog:

32
32 Publications Verification
Cat. No.: HY-D0218
CAS No.: 2390-54-7
Synonyms: Basic Yellow 1
Thioflavin T is a cationic Benzothiazole dye that shows enhanced fluorescence upon binding to amyloid in tissue sections. Excitation max.: ~385 nm (free); ~450 nm (bound); Emission max.: ~445 nm (free); ~485 nm (bound) .
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13
13 Cited Publications
Cat. No.: HY-108896
CAS No.: 138614-30-9
Purity:  99.85%
Synonyms: HOE 140 acetate
Target:  

Bradykinin Receptor

Research Areas:  

Inflammation/Immunology

Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC50 and Ki of 1.07 nM and 0.798 nM respectively .
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1
1 Cited Publications
Cat. No.: HY-W040269
CAS No.: 92-36-4
Synonyms: DHPT
Research Areas:  

Others

Dehydrothio-p-toluidine (DHPT) is a chemical intermediate used in dyestuff production. Dehydrothio-p-toluidine shows inhalation toxicity in acute and subchronic conditions .
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Cat. No.: HY-W012634
CAS No.: 95-16-9
Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent [1][2][3][4].
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Cat. No.: HY-10862
CAS No.: 326866-17-5
Purity:  98.91%
Synonyms: Benzothiazole analog 3
Target:  

FAAH Autophagy

Research Areas:  

Neurological Disease Cancer

FAAH inhibitor 1 (compound 3) is a selective reversible FAAH inhibitor. FAAH inhibitor 1 has no off-target activity with respect to other serine hydrolases. FAAH inhibitor 1 is exclusively specific against FAAH in rat brain with an IC50 value of 18 nM and had no missing protein bands in all the other tissues. FAAH inhibitor 1 can be used for neurological disorders research .
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Cat. No.: HY-DY1049
CAS No.: 2390-54-7
Thioflavin T (solution) is a cationic Benzothiazole dye that shows enhanced fluorescence upon binding to amyloid in tissue sections. Excitation max.: ~385 nm (free) ; ~450 nm (bound) ; Emission max.: ~445 nm (free) ; ~485 nm (bound) .
Solvent and Concentration: Sterile water: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
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Cat. No.: HY-W012634S
CAS No.: 194423-51-3
Benzothiazole-d4 is a deuterium labeled Benzothiazole (HY-W012634). Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral .
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Cat. No.: HY-D2344
CAS No.: 325721-44-6
Synonyms: 3-Benzothiazole-daphnetin
3-BTD (3-Benzothiazole-daphnetin) is a Catechol-O-methyltransferase (COMT) two-photon fluorescence probe. 3-BTD can also be used for biological imaging of endogenous COMT in living cells and tissue sections .
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Cat. No.: HY-W997836
CAS No.: 74923-08-3
Synonyms: 4-AHP
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

4-Amino-3-hydroxyphenylalanine dihydrochloride (4-AHP) is a photodegradation product of eumelanin. 4-Amino-3-hydroxyphenylalanine dihydrochloride can be used to investigate the development of cutaneous melanoma and age-related macular degeneration .
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Cat. No.: HY-134801
CAS No.: 354126-20-8
Purity:  99.74%
Target:  

GPR35

CID1231538, a benzothiazole analog, is a potent GPR35 antagonist with no significant activity against rodent orthologs of GPR35, which is also a G protein-coupled receptor (GPCR) .
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Cat. No.: HY-18402
CAS No.: 615-22-5
Target:  

Drug Derivative

Research Areas:  

Cardiovascular Disease

2-(Methylthio)benzothiazole is a derivative of 2-Mercaptobenzothiazole (HY-W017113). 2-(Methylthio)benzothiazole reduces heart rate, causes pericardial edema and deformity, delays cardiac maturation, decreases stroke volume and cardiac output, and leads to vascular structural defects in zebrafish larvae .
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Cat. No.: HY-145766
CAS No.: 906258-69-3
Purity:  99.14%
Research Areas:  

Others

Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine is an active compound .
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Cat. No.: HY-105084A
CAS No.: 144665-09-8
Purity:  99.00%
Lubeluzole dihydrochloride is the dihydrochloride salt of Lubeluzole (HY-105084). Lubeluzole dihydrochloride is the S-isomer of benzothiazole derivative. Lubeluzole dihydrochloride can inhibit glutamate release, glutamate-activated NO synthesis and block voltage-gated Sodium Channel and Calcium Channel. Lubeluzole dihydrochloride exhibits anti-ischemic and neuroprotective effects. Lubeluzole dihydrochloride also shows anti-bacterial and anti-diarrheal potential. Lubeluzole dihydrochloride can inhibit cardiac sodium channel and prolong cardiac action potential. Lubeluzole dihydrochloride can inhibit cancer cells proliferation and invasion and shows chemosensitizing effect. Lubeluzole dihydrochloride can be used for the researches of cancer, infection, neurological and cardiovascular disease such as stroke, infectious diarrhea and ovarian .
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Cat. No.: HY-W067445
CAS No.: 122-85-0
Synonyms: 4-Acetamidobenzaldehyde
N-(4-Formylphenyl) acetamide (4-Acetamidobenzaldehyde) is an organic ligand bearing aldehyde and acetamide functional groups. N-(4-Formylphenyl) acetamide can be used to functionalize Fe3O4@SiO2 nanoparticles for selective fluorescence quenching detection of Hg 2+. N-(4-Formylphenyl) acetamide serves as a precursor for the synthesis of benzimidazole, benzothiazole and Schiff base derivatives, which exhibit antioxidant, AChE/BChE inhibitory and DNA-binding activities. N-(4-Formylphenyl) acetamide can be applied in studies related to Alzheimer's disease .
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Cat. No.: HY-75577
CAS No.: 2486-69-3
4-Amino-3-methoxybenzoic acid is a drug intermediate that can be used to construct benzothiazole compounds with anti-breast cancer activity .
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Cat. No.: HY-139432
CAS No.: 102-77-2
Purity:  99.21%
Research Areas:  

Others

2-(Morpholinothio)benzothiazole is an accelerator that can be used for amperometric measurements .
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Cat. No.: HY-147973
CAS No.: 2636771-45-2
Target:  

c-Myc Apoptosis

Research Areas:  

Cancer

IZTZ-1, an imidazole-benzothiazole conjugate, is a c-MYC G4 ligand. IZTZ-1 is able to downregulate the c-MYC expression by stabilizing c-MYC G4. IZTZ-1 induces cell cycle arrest, apoptosis, thereby inhibiting cell proliferation in B16 cells. IZTZ-1 shows antitumor activity, and can be used for melanoma research .
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Cat. No.: HY-151581
CAS No.: 2977251-08-2
Target:  

Virus Protease

Research Areas:  

Infection

HCVcc-IN-1 is a benzothiazole-2-thiophene S-glycoside derivative with low toxic and antiviral activity .
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Cat. No.: HY-105084
CAS No.: 144665-07-6
Lubeluzole is the S-isomer of benzothiazole derivative. Lubeluzole can inhibit glutamate release, glutamate-activated NO synthesis and block voltage-gated Sodium Channel and Calcium Channel. Lubeluzole exhibits anti-ischemic and neuroprotective effects. Lubeluzole also shows anti-bacterial and anti-diarrheal potential. Lubeluzole can inhibit cardiac sodium channel and prolong cardiac action potential. Lubeluzole can inhibit cancer cells proliferation and invasion and shows chemosensitizing effect. Lubeluzole can be used for the researches of cancer, infection, neurological and cardiovascular disease such as stroke, infectious diarrhea and ovarian .
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Cat. No.: HY-179415
CAS No.: 1088704-78-2
Research Areas:  

Infection

DHFR-IN-24, a benzothiazole derivative, is a dihydrofolate reductase (DHFR) inhibitor. DHFR-IN-24 has intrinsic antibacterial activity against both Gram-positive and Gram-negative strains. DHFR-IN-24 synergistically combines DHFR inhibition with photodynamic therapy (PDT) for enhanced antibacterial activity against multidrug-resistant pathogens .
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